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STAT1

signal transducer and activator of transcription 1, 91kDa

Synonyms:
CANDF7, ISGF-3, STAT91
Species:
UniProtKB ID:
Gene ID:
  • Human(6772) Summary: The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
  • Mouse(20846) signal transducer and activator of transcription 1
  • Rat(25124) signal transducer and activator of transcription 1
  • dog(488449) signal transducer and activator of transcription 1, 91kDa
  • sheep(100307049) signal transducer and activator of transcription 1, 91kDa
  • cow(510814) signal transducer and activator of transcription 1, 91kDa
  • Domestic Rabbit(100343893) signal transducer and activator of transcription 1, 91kDa
  • domestic guinea pig(100724708) signal transducer and activator of transcription 1, 91kDa
  • naked mole-rat(101718902) signal transducer and activator of transcription 1, 91kDa
  • chicken(424044) signal transducer and activator of transcription 1, 91kDa

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ELISA

Product Number
Description
Species
Phosphotyrosine STAT1 ELISA Kit, ,
Species
human
Phospho-Stat1 (pTyr701) and pan-Stat1 ELISA Kit, for detection of phospho-stat1 (pTyr701) and pan-stat1 in human or mouse cell and tissue lysates,
Species
mouse, human
Cell-Based ELISA for detecting phospho-STAT1 (pTyr701) in cultured cell lines, 96 assays,
Species
mouse, human
Phospho-Stat1 (pSer727) ELISA Kit, for detection of phospho-stat1 (pSer727) in human or mouse cell and tissue lysates,
Species
mouse, human
Phospho-Stat1 (pSer727) and pan-Stat1 ELISA Kit, for detection of phospho-stat1 (pSer727) and pan-stat1 in human or mouse cell and tissue lysates,
Species
mouse, human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-phospho-STAT1 (Ser 727) Antibody, clone 12C5, clone 12C5, Upstate®, from mouse,
Species Reactivity
human
Application
ELISA
western blot
Monoclonal Anti-STAT1 antibody produced in mouse, clone SM2,
Species Reactivity
Application
western blot
Monoclonal Anti-STAT1 antibody produced in mouse, clone SM1,
Species Reactivity
human, mouse
Application
western blot
Anti-STAT1-α Antibody, Chemicon®, from rabbit,
Species Reactivity
human, mouse
Application
immunoprecipitation (IP)
western blot
Anti-phospho-STAT1 (Tyr701) Antibody, Upstate®, from rabbit,
Species Reactivity
chicken, human, mouse, rat
Application
western blot

Cell Lines

Product Number
Description
Species
A549 Cells GFP-STAT1, ,
Species
human

Proteins

Product Number
Description
Species
STAT1 human, recombinant, expressed in insect cells, ≥70% (SDS-PAGE),
Species
human
STAT1 β, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human STAT1,
Species
human
MISSION® esiRNA, targeting mouse Stat1,
Species
mouse