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VEGFA

vascular endothelial growth factor A

Synonyms:
MVCD1, VEGF, VPF
Species:
UniProtKB ID:
Gene ID:
  • Human(7422) Summary: This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(22339) vascular endothelial growth factor A
  • Rat(83785) vascular endothelial growth factor A
  • domestic cat(493845) vascular endothelial growth factor A
  • cow(281572) vascular endothelial growth factor A
  • sheep(443103) vascular endothelial growth factor A
  • Goat(100860957) vascular endothelial growth factor A
  • Domestic Rabbit(100008899) vascular endothelial growth factor A
  • domestic guinea pig(100713483) vascular endothelial growth factor A
  • domestic guinea pig(100462897) vascular endothelial growth factor A
  • naked mole-rat(101702403) vascular endothelial growth factor A
  • chicken(395909) vascular endothelial growth factor A
  • dog(403802) vascular endothelial growth factor A
  • Horse(100033839) vascular endothelial growth factor A

Custom & Knockdown Gene Products

ELISA

Product Number
Description
Species
Human VEGF-A ELISA Kit, for serum, plasma, cell culture supernatants and urine,
Species
human
Canine VEGFA / Vascular Endothelial Growth Factor A ELISA Kit, ,
Species
dog
Porcine VEGF-A ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Species
Bovine VEGF-A ELISA, for serum, plasma and cell culture supernatants,
Species
cow
Equine VEGF-A ELISA, for serum, plasma and cell culture supernatants,
Species
horse

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-VEGF Antibody, Alexa Fluor 647 Conjugate, from rabbit, ALEXA FLUOR 647,
Species Reactivity
human, mouse, nonhuman primates, rat
Application
immunocytochemistry
Anti-Vascular Endothelial Growth Factor antibody produced in goat, affinity isolated antibody, lyophilized powder,
Species Reactivity
mouse
Application
ELISA
immunohistochemistry

neutralization

western blot
Anti-Vascular Endothelial Growth Factor antibody produced in goat, IgG fraction of antiserum, lyophilized powder,
Species Reactivity
human
Application
immunohistochemistry
neutralization

western blot
Anti-VEGF-A Antibody, clone 2C4 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human
Application
ELISA
affinity binding assay

flow cytometry

western blot
Anti-VEGFA antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunoprecipitation (IP)

western blot

Small Molecule - Inhibitor

Product Number
Description
Species
Tranilast, ≥98% (HPLC), powder,
Species
human

Proteins

Product Number
Description
Species
Vascular Endothelial Growth Factor 165 human, VEGF165, recombinant, expressed in HEK 293 cells, HumanKine®, suitable for cell culture,
Species
human
Vascular Endothelial Growth Factor 164 from rat, >95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder,
Species
rat
VEGF165, recombinant, expressed in HEK 293 cells, suitable for cell culture,
Species
human
SILuLite VEGFA Vascular endothelial growth factor A human, recombinant, expressed in HEK 293 cells, MS Protein Standard,
Species
human
Vascular Endothelial Growth Factor 121 human, VEGF121, recombinant, expressed in HEK 293 cells, HumanKine®, suitable for cell culture,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Vegfa,
Species
mouse
MISSION® esiRNA, targeting human VEGFA,
Species
human