MX1394

1-Methyl-2-pyrrolidone

for Peptide Synthesis

• Synonym(s): 1-Methyl-2-Pyrrolidone, 1-Methyl-2-pyrrolidinone,NMP
• Linear Formula: (CH₃)-NC(=O)CH₂CH₂CH₂-
• CAS Number: 872-50-4
• MDL number: MFCD00003193
• UNSPSC Code: 12352115
• EC Index Number: 212-828-1

Properties

• vapor pressure: 0.32 hPa ( 20 °C)
• Quality Level: 200
• assay: ≥99.5% (GC)
• form: liquid
• impurities: ≤1 ppm Heavy metals (as Pb); ≤1.0 μeq/g Titrable base; ≤300 ppm Water (H2O); ≤5 ppm Free amine (as dimethylamine)
• color: clearAPHA: ≤20
• pH: 8.5-10.0 (20 °C, 100 g/L in H₂O)
• bp: 202 °C/1013 hPa
• mp: -24 °C
• transition temp: flash point 91 °C
• solubility: 1000 g/L
• density: 1.03 g/cm³ at 20 °C
• UV cutoff: ≤275 nm
• UV absorption: λ: 275 nm A_max: ≤1.00; λ: 280 nm A_max: ≤0.70; λ: 300 nm A_max: ≤0.30; λ: 350 nm A_max: ≤0.10; λ: 400 nm A_max: ≤0.01
• application(s): peptide synthesis
• shipped in: ambient
• storage temp.: room temp
• InChI: 1S/C5H9NO/c1-6-4-2-3-5(6)7/h2-4H2,1H3
• InChI key: SECXISVLQFMRJM-UHFFFAOYSA-N

Description

Application

for Peptide Synthesis

Preparation Note

Product filtered through a 0.2 μm filter

Analysis Note

AppearanceClear, free from particulatesAssay (GC)99.5% minColor (APHA)20 maxFiltered through 0.2 µm filterTo pass testFormLiquidFree amine (as dimethylamine)5ppm maxHeavy metals (as Pb)1ppm maxResidue after ignition10ppm maxTitrable base1.0µeq/g maxUV Abs. at 275 nm1.00AU maxUV Abs. at 280 nm0.70AU maxUV Abs. at 300 nm0.30AU maxUV Abs. at 350 nm0.10AU maxUV Abs. at 400 nm0.01AU maxUV Cut-off275nm maxWater (H2O)300ppm max

Safety Information

• pictograms: GHS08,GHS07
• signalword: Danger
• hcodes: H315,H319,H335,H360D
• pcodes: P202 - P261 - P264 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• wgk_germany: WGK 1