16005

Brij^® L23

main component: tricosaethylene glycol dodecyl ether

• Synonym(s): Brij 35, C₁₂E₂₃, Polyoxyethylene (23) lauryl ether
• CAS Number: 9002-92-0
• MDL number: MFCD00080891
• PubChem Substance ID: 57647536
• NACRES: NA.21

Properties

• Quality Level: 200
• description: non-ionic
• form: pellets
• CMC: 91 μM
• mp: 39-43 °C
• HLB value: 16.9
• solubility: H₂O: 40 mg/mL at 20 °C, clear to slightly hazy, colorless
• cation traces: Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤500 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Na: ≤500 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Zn: ≤5 mg/kg
• SMILES string: CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO
• InChI: 1S/C58H118O24/c1-2-3-4-5-6-7-8-9-10-11-13-60-15-17-62-19-21-64-23-25-66-27-29-68-31-33-70-35-37-72-39-41-74-43-45-76-47-49-78-51-53-80-55-57-82-58-56-81-54-52-79-50-48-77-46-44-75-42-40-73-38-36-71-34-32-69-30-28-67-26-24-65-22-20-63-18-16-61-14-12-59/h59H,2-58H2,1H3
• InChI key: IEQAICDLOKRSRL-UHFFFAOYSA-N

Description

Application

Brij^®L23 is a detergent used for measuring the concentration of carbon black in lung tissues.[1] It has also been used for selective and rapid solubilization of microbial membrane aldehyde dehydrogenase.[2] Additionally, the product has also been used for assessing whether acrolein could lead to pro-enzyme activation by using gelatin zymography.[3]

Biochem/physiol Actions

Brij^® L23 also referred to as Brij 35 or Polyoxyethylene (23) lauryl ether is a non-ionic detergent that lowers the non-specific protein adsorption and reduces electroosmotic pumping drastically.[4] This allows the pH to be varied without adversely affecting the flow rate. It also used as a nonionic surfactant that decreases the absorbance of the blank, inhibits turbidity as well as provides linearity.[5]

Other Notes

Non-ionic polyoxyethylene ether.[6] Used for selective and rapid solubilization of microbial membrane aldehyde dehydrogenase.[2]

Legal Information

Brij is a registered trademark of Croda International PLC

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): 300.2 °F - open cup
• Flash Point(C): > 149 °C - open cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves