E0502

Sigma-Aldrich

Elastin–Congo red

elastase substrate

MDL number:
NACRES:
NA.32
Pricing and availability is not currently available.

Quality Level

form

powder

storage temp.

2-8°C

General description

Elastin−Congo red is a substrate-dye conjugate and is used in agar medium to probe elastase activity. The presence of elastase functionality leads to cleavage of the dye from the elastin substrate.

Application

Elastin−Congo red has been used as a substrate for neutrophil elastase, salivary elastase and P. aeruginosa.

Packaging

5 g in glass bottle

Other Notes

Elastin impregnated with Congo red dye.

Substrates

Substrate for the estimation of elastase.

Pictograms

Health hazard

Signal Word

Danger

Hazard Statements

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
AiiM lactonase strongly reduces quorum sensing controlled virulence factors in clinical strains of Pseudomonas aeruginosa isolated from burned patients
Lopez-Jacome LE, et al.
Frontiers in Microbiology, 10, 2657-2657 (2019)
Salivary immunity in elderly individuals presented with Candida-related denture stomatitis
Gasparoto T, et al.
Gerodontology, 29(2), e331-e339 (2012)
Development of an agar diffusion method to measure elastase inhibition activity using Elastin-Congo red
Jung KH and Kim HJ
Journal of microbiology and biotechnology, 16(8), 1320-1324 (2006)
Activation pattern of neutrophils from blood of elderly individuals with Candida-related denture stomatitis
Gasparoto TH, et al.
European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology, 31(6), 1271-1277 (2012)
Martina Ramella et al.
American journal of translational research, 9(12), 5485-5495 (2018-01-10)
Progression of abdominal aortic aneurysm (AAA) is typified by chronic inflammation and extracellular matrix (ECM) degradation of the aortic wall. Vascular inflammation involves complex interactions among inflammatory cells, endothelial cells (ECs), vascular smooth muscle cells (vSMCs), and ECM. Although vascular...
Articles
Enzyme Explorer Product Application Index for Elastase. Leukocyte elastase is a 29KDa serine endoprotease of the Proteinase S1 Family. It exists as a single 238 amino acid-peptide chain with four disulfide bonds.
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Protocols
Our General Protease Assay Procedures and Substrates overview.
Read More

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