- Crystal structure, spectroscopic, and biological study of the copper(II) complex with third-generation quinolone antibiotic sparfloxacin.
Crystal structure, spectroscopic, and biological study of the copper(II) complex with third-generation quinolone antibiotic sparfloxacin.
Bioorganic & medicinal chemistry letters (2006-05-16)
Eleni K Efthimiadou, Yiannis Sanakis, Catherine P Raptopoulou, Alexandra Karaliota, Nikos Katsaros, George Psomas
PMID16697195
RESUMEN
The neutral mononuclear copper(II) complex with the quinolone antibacterial drug sparfloxacin has been prepared and characterized with IR, UV-vis, and EPR spectroscopies and X-ray crystallography. The interaction of the complex with calf-thymus DNA has also been investigated and the antimicrobial activity has been evaluated against three different microorganisms.