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  • PEG-immobilization of cardol and soluble polymer-supported synthesis of some cardol-coumarin derivatives: preliminary evaluation of their inhibitory activity on mushroom tyrosinase.

PEG-immobilization of cardol and soluble polymer-supported synthesis of some cardol-coumarin derivatives: preliminary evaluation of their inhibitory activity on mushroom tyrosinase.

Bioorganic & medicinal chemistry letters (2008-12-05)
Graziella Tocco, Antonella Fais, Gabriele Meli, Michela Begala, Gianni Podda, M Benedetta Fadda, Marcella Corda, Orazio A Attanasi, Paolino Filippone, Stefano Berretta
RESUMEN

In this work, the PEG-immobilization and the liquid phase synthesis of some coumarins derived from cardol are presented. Some preliminary results on their tyrosinase inhibitory activity are also included.

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