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Lanostane and hopane triterpenes from the entomopathogenic fungus Hypocrella sp. BCC 14524.

Journal of natural products (2011-10-15)
Masahiko Isaka, Panida Chinthanom, Malipan Sappan, Rungtiwa Chanthaket, J Jennifer Luangsa-ard, Samran Prabpai, Palangpon Kongsaeree
RESUMEN

Seven new lanostane-type triterpenes, hypocrellols A-G (1-7), and six new hopane-type triterpenes, 7β,15α-dihydroxy-22(29)-hopene (8), 3β,7β-dihydroxy-22(29)-hopene (9), 3β-acetoxy-15α-hydroxy-22(29)-hopene (10), 3β,7β,15α,22-tetrahydroxyhopane (11), 3β-acetoxy-7β,15α,22-trihydroxyhopane (12), and 7β,15α,22-trihydroxyhopane (13), were isolated from the scale insect pathogenic fungus Hypocrella sp. BCC 14524. The structures of the new compounds were elucidated by analyses of the NMR spectroscopic and mass spectrometry data. The structure of 1 was confirmed by X-ray crystallography.

MATERIALES
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Sigma-Aldrich
Doxorrubicina hydrochloride, 98.0-102.0% (HPLC)
Sigma-Aldrich
Doxorrubicina hydrochloride, suitable for fluorescence, 98.0-102.0% (HPLC)
Supelco
Isoniazid, analytical standard, ≥99% (TLC)
Supelco
17α(H),21β(H)-Hopane solution, 0.1 mg/mL in isooctane, analytical standard
Supelco
17β(H),21β(H)-Hopane solution, 0.1 mg/mL in isooctane, analytical standard