- Rigid Mn(II) chelate as efficient MRI contrast agent for vascular imaging.
Rigid Mn(II) chelate as efficient MRI contrast agent for vascular imaging.
Dalton transactions (Cambridge, England : 2003) (2012-10-31)
Hongying Su, Changqiang Wu, Jiang Zhu, Tianxin Miao, Dan Wang, Chunchao Xia, Xuna Zhao, Qiyong Gong, Bin Song, Hua Ai
PMID23108333
RESUMEN
The aza-semi-crown pentadentate ligand rigidified by pyridine and piperidine rings was designed and synthesized. It can react with Mn(II) in water to form complex with improved longitudinal relaxivity, leading to efficient signal intensity enhancement of vascular vessels under a clinical magnetic resonance imaging scanner.
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