Arylation of 2-substituted pyridines via Pd-catalyzed decarboxylative cross-coupling reactions of 2-picolinic acid.

Arylation of 2-substituted pyridines via Pd-catalyzed decarboxylative cross-coupling reactions of 2-picolinic acid.

Chemical communications (Cambridge, England) (2012-11-23)

Xinjian Li, Dapeng Zou, Faqiang Leng, Chunxia Sun, Jingya Li, Yangjie Wu, Yusheng Wu

RESUMEN

The novel palladium-catalyzed decarboxylative cross-coupling reactions of 2-picolinic acid with aryl and heteroaryl bromides including benzenes, naphthalenes, pyridines and quinolines for C-C bond formation have been successfully achieved.

MATERIALES

Número de producto

Marca

Descripción del producto

147141

Sigma-Aldrich

Naphthalene, 99%

P42800

Sigma-Aldrich

2-Picolinic acid, ReagentPlus^®, 99%

84679

Supelco

Naphthalene, analytical standard

184500

Sigma-Aldrich

Naphthalene, suitable for scintillation, ≥99%

01422

Supelco

Melting point standard 79.5-81°C, analytical standard

40053

Supelco

Naphthalene solution, certified reference material, 5000 μg/mL in methanol

91489

Supelco

Naphthalene, certified reference material, TraceCERT^®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland