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[Stimulatory effect of sodium deoxycholate on alpha-ergocryptine productivity of Claviceps purpurea 94002 (EKPN94002)].

Yao xue xue bao = Acta pharmaceutica Sinica (1997-08-01)
P Zhu, H X He, S Z Chen
RESUMEN

The stimulation of sodium deoxycholate (SDC) on alpha-ergocryptine production of Claviceps purpurea strain 94002 (EKPN94002) was investigated. Preliminary results indicated that SDC, as a stimulator and at appropriate concentrations, could obviously increase the extracellular and the total production levels of the ergot alkaloid. Satisfied results were obtained when 6.0 mg.L-1 of SDC was present in the seed and fermentation media. The possible mechanism was discussed.