Smart soft-templating synthesis of hollow mesoporous bioactive glass spheres.

Smart soft-templating synthesis of hollow mesoporous bioactive glass spheres.

Chemistry (Weinheim an der Bergstrasse, Germany) (2015-04-23)

Yunqi Li, Bishnu Prasad Bastakoti, Yusuke Yamauchi

RESUMEN

Hollow bioactive glass spheres with mesoporous shells were prepared by using dual soft templates, a diblock co-polymer poly(styrene-b-acrylic acid) (PS-b-PAA) and a cationic surfactant cetyltrimethylammonium bromide (CTAB). Hollow mesoporous bioactive glass (HMBG) spheres comprise the large hollow interior with vertical mesochannels in shell, which realize large uptake of drugs and their sustained release. The formation of hydroxyapatite layer on the surface of HMBG particles shows the clear evidence for promising application in bone regeneration.

MATERIALES

Número de producto

Marca

Descripción del producto

401757

Sigma-Aldrich

Tetrahidrofuran, anhydrous, ≥99.9%, inhibitor-free

186562

Sigma-Aldrich

Tetrahidrofuran, anhydrous, contains 250 ppm BHT as inhibitor, ≥99.9%

S5761

Sigma-Aldrich

Bicarbonato de sodio, powder, BioReagent, Molecular Biology, suitable for cell culture, suitable for insect cell culture

459836

Sigma-Aldrich

Alcohol etílico puro, 200 proof, anhydrous, ≥99.5%

M1028

Sigma-Aldrich

Magnesium chloride solution, Molecular Biology, 1.00 M±0.01 M

H5882

Sigma-Aldrich

Bromuro de hexadeciltrimetilamonio, ≥98%

S3014

Sigma-Aldrich

Cloruro de sodio, Molecular Biology, DNase, RNase, and protease, none detected, ≥99% (titration)

M8266

Sigma-Aldrich

Magnesium chloride, ≥98%

H9892

Sigma-Aldrich

Ácido clorhídrico solution, 1.0 N, BioReagent, suitable for cell culture

S5150

Sigma-Aldrich

Sodium chloride solution, 5 M in H₂O, BioReagent, Molecular Biology, suitable for cell culture

S7653

Sigma-Aldrich

Cloruro de sodio, BioXtra, ≥99.5% (AT)

S5886

Sigma-Aldrich

Cloruro de sodio, BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture, ≥99%

S8776

Sigma-Aldrich

Sodium chloride solution, 0.9% in water, BioXtra, suitable for cell culture

P9541

Sigma-Aldrich

Cloruro de potasio, Molecular Biology, ≥99.0%

H6269

Sigma-Aldrich

Bromuro de hexadeciltrimetilamonio, Molecular Biology, ≥99%

P5405

Sigma-Aldrich

Cloruro de potasio, powder, BioReagent, suitable for cell culture, suitable for insect cell culture, ≥99.0%

493511

Sigma-Aldrich

Alcohol etílico puro, 190 proof, ACS spectrophotometric grade, 95.0%

H1758

Sigma-Aldrich

Ácido clorhídrico, 36.5-38.0%, BioReagent, Molecular Biology

S6546

Sigma-Aldrich

Sodium chloride solution, 5 M

59222C

SAFC

Sodium chloride solution, 5 M

2104

Supelco

Ácido clorhídrico solution, volumetric, 0.1 M HCl (0.1N), endotoxin free

208337

Sigma-Aldrich

Magnesium chloride, powder, <200 μm

538728

Sigma-Aldrich

Triethyl phosphate, ReagentPlus^®, ≥99.8%

60142

Sigma-Aldrich

Cloruro de potasio solution, BioUltra, Molecular Biology, ~1 M in H₂O

28-2270

Sigma-Aldrich

Cloruro de sodio, JIS special grade, ≥99.5%

H9151

Sigma-Aldrich

Bromuro de hexadeciltrimetilamonio, BioXtra, ≥99%

60353

Sigma-Aldrich

Fosfato de potasio dibasic, anhydrous, suitable for luminescence, Molecular Biology, BioUltra, ≥99.0% (T)

493538

Sigma-Aldrich

Alcohol etílico puro, 190 proof, meets USP testing specifications

71376

Sigma-Aldrich

Cloruro de sodio, BioUltra, Molecular Biology, ≥99.5% (AT)

13-1650

Sigma-Aldrich

Ácido clorhídrico, SAJ first grade, 35.0-37.0%