- miR-589-5p inhibits MAP3K8 and suppresses CD90
miR-589-5p inhibits MAP3K8 and suppresses CD90
Journal of experimental & clinical cancer research : CR (2016-11-12)
Xi Zhang, Peng Jiang, Ling Shuai, Kai Chen, Zhonghu Li, Yujun Zhang, Yan Jiang, Xiaowu Li
PMID27835990
RESUMEN
Cancer stem cells (CSCs) are important in the tumorigenesis and progression of hepatocellular carcinoma (HCC). MicroRNAs (miRNAs) play crucial roles regulating CD133 The miRNA profiles of CD90 miR-589-5p and miR-33b-5p were down-regulated in CD90 In HCC, miR-589-5p down-regulates the stemness characteristics of CD90