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Merck

31170

2-Deoxy-D-ribose

≥99.0% (TLC)

Synonym(s):

2-Deoxy-D-arabinose, 2-Deoxy-D-erythropentose, Thyminose

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5 G

R 2,218.72

25 G

R 7,091.28

R 2,218.72

List PriceR 2,264.00

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About This Item

Empirical Formula (Hill Notation):
C5H10O4
CAS Number:
Molecular Weight:
134.13
UNSPSC Code:
12352201
NACRES:
NA.25
PubChem Substance ID:
EC Number:
208-573-0
Beilstein/REAXYS Number:
1721978
MDL number:

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Product Name

2-Deoxy-D-ribose, ≥99.0% (TLC)

InChI key

ASJSAQIRZKANQN-CRCLSJGQSA-N

InChI

1S/C5H10O4/c6-2-1-4(8)5(9)3-7/h2,4-5,7-9H,1,3H2/t4-,5+/m0/s1

SMILES string

OC[C@@H](O)[C@@H](O)CC=O

assay

≥99.0% (TLC)

form

solid

optical activity

[α]20/D −56±2°, 24 hr, c = 1% in H2O

impurities

<0.5% Sulphated ash

ign. residue

≤0.5% (as SO4)

loss

≤1% loss on drying, 20 °C (HV)

color

white

mp

89-90 °C (lit.)

solubility

water: 50 mg/mL, clear, colorless to faintly yellow

storage temp.

2-8°C

Quality Level

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1 of 4

This Item
121649D589975617
assay

≥99.0% (TLC)

assay

97% (GC)

assay

≥99% (GC)

assay

≥97.0% (TLC)

Quality Level

200

Quality Level

100

Quality Level

200

Quality Level

100

solubility

water: 50 mg/mL, clear, colorless to faintly yellow

solubility

-

solubility

water: 100 mg/mL, clear to slightly hazy, colorless to light yellow

solubility

-

form

solid

form

powder

form

powder

form

powder

storage temp.

2-8°C

storage temp.

-

storage temp.

2-8°C

storage temp.

2-8°C

impurities

<0.5% Sulphated ash

impurities

-

impurities

-

impurities

-

Application

2-Deoxy-D-ribose is used to study processes of oxidative stress and glycation in vivo and in vitro. 2-Deoxy-D-ribose, an endothelial-cell chemoattractant and angiogenesis-inducing factor, is used to study processes of tumor angiogenesis and progression mediated at the level of thymidine phosphorylase activity.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Tymofii Yu Nikolaienko et al.
Physical chemistry chemical physics : PCCP, 14(44), 15554-15561 (2012-10-18)
Relaxed force constants (RFC) and vibrational root-mean-square (VRMS) deviations are used for comparative characterization of mechanical properties of canonical 2'-deoxyribonucleosides (2DRs) and 1,2-dideoxyribose molecule, their model sugar residue. It has been shown that RFC and VRMS should be preferred over
Anita R Peoples et al.
Nucleic acids research, 40(13), 6060-6069 (2012-04-03)
Our mechanistic understanding of damage formation in DNA by the direct effect relies heavily on what is known of free radical intermediates studied by EPR spectroscopy. Bridging this information to stable product formation requires methods with comparable sensitivities, a criterion
Manuel Ellermann et al.
Acta crystallographica. Section D, Biological crystallography, 68(Pt 3), 253-260 (2012-02-22)
The biological activity of catechol neurotransmitters such as dopamine in the synapse is modulated by transporters and enzymes. Catechol-O-methyltransferase (COMT; EC 2.1.1.6) inactivates neurotransmitters by catalyzing the transfer of a methyl group from S-adenosylmethionine to catechols in the presence of
Adam J Stevens et al.
Biochemistry, 52(5), 975-983 (2013-01-22)
Base excision repair (BER) plays a vital role in maintaining genomic integrity in mammalian cells. DNA polymerase λ (Pol λ) is believed to play a backup role to DNA polymerase β (Pol β) in base excision repair. Two oxidized abasic
Katarzyna Lamparska et al.
Nucleic acids research, 40(19), 9788-9801 (2012-08-02)
5-Aza-2'-deoxycytidine (5azaC-dR) has been employed as an inhibitor of DNA methylation, a chemotherapeutic agent, a clastogen, a mutagen, an inducer of fragile sites and a carcinogen. However, its effects are difficult to quantify because it rapidly breaks down in aqueous

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