Przejdź do zawartości
Merck

ANGPTL4

angiopoietin-like 4

Synonimy:
ANGPTL2, ARP4, FIAF, HARP, HFARP, NL2, PGAR, UNQ171, pp1158
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(51129) Summary: This gene is a member of the angiopoietin/angiopoietin-like gene family and encodes a glycosylated, secreted protein with a fibrinogen C-terminal domain. This gene is induced under hypoxic conditions in endothelial cells and is the target of peroxisome proliferation activators. The encoded protein is a serum hormone directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity and also acts as an apoptosis survival factor for vascular endothelial cells. The encoded protein may play a role in several cancers and it also has been shown to prevent the metastatic process by inhibiting vascular activity as well as tumor cell motility and invasiveness. Decreased expression of this protein has been associated with type 2 diabetes. Alternatively spliced transcript variants encoding different isoforms have been described. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4. [provided by RefSeq, Jul 2008]
  • Mouse(57875) angiopoietin-like 4
  • Rat(362850) angiopoietin-like 4
  • Zebrafish(492647) angiopoietin-like 4
  • chicken(769087) angiopoietin-like 4
  • cow(509963) angiopoietin-like 4
  • domestic cat(101090747) angiopoietin-like 4
  • sheep(101104317) angiopoietin-like 4
  • Goat(100860916) angiopoietin-like 4
  • naked mole-rat(101718658) angiopoietin-like 4
  • domestic guinea pig(100733453) angiopoietin-like 4
  • dog(476724) angiopoietin-like 4

Custom & Knockdown Gene Products

ELISA

Numer produktu
Opis
Gatunek
Human ANGPTL4 ELISA Kit, for serum, plasma and cell culture supernatants,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Monoclonal Anti-ANGPTL4, (C-terminal) antibody produced in mouse, clone 1A12, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunoprecipitation (IP)
Przeciwciało anty-ANGPTL4 (MID), clone ZMD.521, Chemicon®, from rabbit,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
western blot

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human ANGPTL4,
Gatunek
human
MISSION® esiRNA, targeting mouse Angptl4,
Gatunek
mouse