CASP9
caspase 9, apoptosis-related cysteine peptidase
Synonimy:
APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56
Gatunek:
Human CASP9 (842), Mouse Casp9 (12371), Rat Casp9 (58918), domestic cat CASP9 (768260), naked mole-rat Casp9 (101702898), cow CASP9 (100140945), Horse CASP9 (100054331), dog CASP9 (487432), chicken CASP9 (426970), sheep CASP9 (101110953) ...Więcej
Identyfikator UniProtKB:
Identyfikator genu:
- Human(842) Summary: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
- Mouse(12371) caspase 9
- Rat(58918) caspase 9, apoptosis-related cysteine peptidase
- domestic cat(768260) caspase 9, apoptosis-related cysteine peptidase
- naked mole-rat(101702898) caspase 9, apoptosis-related cysteine peptidase
- cow(100140945) caspase 9, apoptosis-related cysteine peptidase
- Horse(100054331) caspase 9, apoptosis-related cysteine peptidase
- dog(487432) caspase 9, apoptosis-related cysteine peptidase
- chicken(426970) caspase 9, apoptosis-related cysteine peptidase
- sheep(101110953) caspase 9, apoptosis-related cysteine peptidase
- domestic guinea pig(100714954) caspase 9, apoptosis-related cysteine peptidase
- Zebrafish(492763) caspase 9, apoptosis-related cysteine protease
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Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-CASP9 (Cleaved-Asp330), C-Terminal antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Caspase-9 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Monoclonal Anti-CASP9 antibody produced in mouse, clone 3B8-4G2, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunofluorescence
proximity ligation assay
western blot
immunofluorescence
proximity ligation assay
western blot
Anti-CASP9 (CLEAVED-ASP353), C-Terminal antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
mouse, rat
Zastosowanie
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Przeciwciało anty-Caspase9 produkowane u królików, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Small Molecule - Inhibitor
Kits
Numer produktu
Opis
Gatunek
Caspase 9 Colorimetric Activity Assay Kit, LEHD, Caspase-9 Colorimetric Activity Assay Kits provide a simple & convenient means for assaying the activity of caspases that recognize the LEHD.,
Gatunek
human
Caspase 9 Colorimetric Activity Assay Kit, LEHD, Caspase-9 Colorimetric Activity Assay Kits provide a simple & convenient means for assaying the activity of caspases that recognize the LEHD.,
Gatunek
human
esiRNA
Small Molecule - Substrate
Numer produktu
Opis
Gatunek
N-Acetyl-Leu-Glu-His-Asp-7-amido-4-trifluoromethylcoumarin, ≥95% (HPLC), powder,
Gatunek
mouse, rat, human