DHFR
dihydrofolate reductase
別名:
DHFRP1, DYR
Species:
Human DHFR (1719), Mouse Dhfr (13361), Rat Dhfr (24312), fruit fly Dhfr (42003), Zebrafish dhfr (81882), domestic guinea pig Dhfr (100729225), naked mole-rat Dhfr (101701790), domestic cat DHFR (101087964), cow DHFR (508809), dog DHFR (609048) ...詳細
UniProtKB ID:
遺伝子ID:
- Human(1719) Summary: Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia. [provided by RefSeq, Jul 2008]
- Mouse(13361) dihydrofolate reductase
- Rat(24312) dihydrofolate reductase
- fruit fly(42003) Dihydrofolate reductase
- Zebrafish(81882) dihydrofolate reductase
- domestic guinea pig(100729225) dihydrofolate reductase
- naked mole-rat(101701790) dihydrofolate reductase
- domestic cat(101087964) dihydrofolate reductase
- cow(508809) dihydrofolate reductase
- dog(609048) dihydrofolate reductase
- chicken(427317) dihydrofolate reductase
- Domestic Rabbit(100359209) dihydrofolate reductase
- sheep(101121421) dihydrofolate reductase
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Activity Assay
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Species
Antibodies
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交差性
アプリケーション
Monoclonal Anti-DHFR antibody produced in mouse, clone 2B10, purified immunoglobulin, buffered aqueous solution,
交差性
human, mouse, rat
アプリケーション
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
抗DHFR, C末端抗体 ウサギ宿主抗体, 1.0-1.5 mg/mL, affinity isolated antibody, buffered aqueous solution,
交差性
human, mouse, rat
アプリケーション
immunoprecipitation (IP)
western blot
western blot
Anti-DHFR, N-terminal antibody produced in rabbit, ~1.0 mg/mL, affinity isolated antibody, buffered aqueous solution,
交差性
human, mouse, rat
アプリケーション
immunoprecipitation (IP)
western blot
western blot
Small Molecule - Inhibitor
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Species
Kits
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Species
Proteins
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Species
ジヒドロ葉酸レダクターゼ ヒト, ≥80% (SDS-PAGE), recombinant, expressed in E. coli, ≥1 units/mg protein,
Species
human
esiRNA
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Species