GREM1
gremlin 1, DAN family BMP antagonist
Sinónimos:
CKTSF1B1, DAND2, DRM, GREMLIN, IHG-2
Especie:
Human GREM1 (26585), Mouse Grem1 (23892), Rat Grem1 (50566), Goat GREM1 (100860969), chicken GREM1 (395826), dog GREM1 (487475), domestic cat GREM1 (101096735), sheep GREM1 (101102396), domestic guinea pig Grem1 (100730568), naked mole-rat Grem1 (101720734)
ID UniProtKB:
ID del gen:
- Human(26585) Summary: This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to relay the sonic hedgehog (SHH) signal from the polarizing region to the apical ectodermal ridge during limb bud outgrowth. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
- Mouse(23892) gremlin 1
- Rat(50566) gremlin 1
- Goat(100860969) gremlin 1
- chicken(395826) gremlin 1
- dog(487475) gremlin 1
- domestic cat(101096735) gremlin 1
- sheep(101102396) gremlin 1
- domestic guinea pig(100730568) gremlin 1, DAN family BMP antagonist
- naked mole-rat(101720734) gremlin 1, DAN family BMP antagonist
- cow(539079) gremlin 1
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Antibodies
Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-Grem1 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
bovine, canine, goat, guinea pig, horse, human, mouse, rabbit, rat, zebrafish
Aplicación
western blot
Anti-Grem1 (C-terminal) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
bovine, canine, goat, guinea pig, horse, human, mouse, rabbit, zebrafish
Aplicación
western blot
Anti-Gremlin-1 Antibody, clone 2H1.1, clone 2H1.1, from mouse,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
western blot
Anti-Grem1 (C-terminal) antibody produced in rabbit FITC conjugated, affinity isolated antibody,
Reactividad de especies
bovine, canine, goat, guinea pig, horse, human, mouse, rabbit, zebrafish
Aplicación
Anti-Grem1 (C-terminal) antibody produced in rabbit HRP conjugated, affinity isolated antibody,
Reactividad de especies
bovine, canine, goat, guinea pig, horse, human, mouse, rabbit, zebrafish
Aplicación