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Merck

GRIK1

glutamate receptor, ionotropic, kainate 1

Sinónimos:
EAA3, EEA3, GLR5, GLUR5, GluK1
Especie:
ID UniProtKB:
ID del gen:
  • Human(2897) Summary: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to alter the properties of ion flow. Alternative splicing, resulting in transcript variants encoding different isoforms, has been noted for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(14805) glutamate receptor, ionotropic, kainate 1
  • Rat(29559) glutamate receptor, ionotropic, kainate 1
  • naked mole-rat(101705989) glutamate receptor, ionotropic, kainate 1
  • dog(487719) glutamate receptor, ionotropic, kainate 1
  • chicken(418489) glutamate receptor, ionotropic, kainate 1
  • Thale Cress(823660) serine/threonine-protein kinase GRIK1
  • cow(533760) glutamate receptor, ionotropic, kainate 1
  • domestic cat(101097165) glutamate receptor, ionotropic, kainate 1
  • Horse(100053602) glutamate receptor, ionotropic, kainate 1
  • domestic guinea pig(100735908) glutamate receptor, ionotropic, kainate 1
  • Domestic Rabbit(100354052) glutamate receptor, ionotropic, kainate 1
  • sheep(101107319) glutamate receptor, ionotropic, kainate 1

Custom & Knockdown Gene Products

Small Molecule - Agonist

Número de producto
Descripción
Especie
L-Glutamic acid hydrochloride, ≥99% (HPLC),
Especie
human
Quisqualic acid, powder,
Especie
rat
N-Methyl-D-aspartic acid, ≥98% (TLC), solid,
Especie
human, rat
(±)-AMPA, solid,
Especie
rat
(S)-AMPA, ≥97%,
Especie
mouse, human, rat

Small Molecule - Antagonist

Número de producto
Descripción
Especie
NS3694, ≥98%, powder,
Especie
human
DL-2-Amino-5-phosphonopentanoic acid, solid,
Especie
rat
2,3-Dihydroxyquinoxaline, 98%,
Especie
rat
DL-2-Amino-5-phosphonovaleric acid lithium salt, ~95%,
Especie
rat
CNQX, ≥98% (HPLC), solid,
Especie
rat

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-Glutamate Receptor 5, 6, 7 Antibody, clone 4F5, ascites fluid, clone 4F5, Chemicon®,
Reactividad de especies
human, monkey, rat
Aplicación
ELISA
immunocytochemistry

immunohistochemistry

radioimmunoassay
Anti-Grik1 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence

Small Molecule - Mixed Agonist/Antagonist

Número de producto
Descripción
Especie
(±)-AMPA, solid,
Especie
rat
Ácido kaínico monohydrate, ≥99% (TLC),
Especie
human, mouse, rat
L-Glutamic acid, ReagentPlus®, ≥99% (HPLC),
Especie
rat, human
L-Glutamic acid, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
Especie
rat, human
L-Glutamic acid, BioUltra, ≥99.5% (NT),
Especie
rat, human