KCNA1
potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
Synonymes:
AEMK, EA1, HBK1, HUK1, KV1.1, MBK1, MK1, RBK1
Espèce(s):
Human KCNA1 (3736), Mouse Kcna1 (16485), Rat Kcna1 (24520), cow KCNA1 (538703), domestic cat KCNA1 (101093364), Horse KCNA1 (100051648), dog KCNA1 (486732), Zebrafish kcna1 (327087), chicken KCNA1 (428101), domestic guinea pig Kcna1 (100731979) ...Plus
ID UniProtKB:
ID du gène:
- Human(3736) Summary: This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK). [provided by RefSeq, Jul 2008]
- Mouse(16485) potassium voltage-gated channel, shaker-related subfamily, member 1
- Rat(24520) potassium voltage-gated channel, shaker-related subfamily, member 1
- cow(538703) potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
- domestic cat(101093364) potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
- Horse(100051648) potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
- dog(486732) potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
- Zebrafish(327087) potassium voltage-gated channel, shaker-related subfamily, member 1
- chicken(428101) potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
- domestic guinea pig(100731979) potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
- Domestic Rabbit(100037722) potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
- Domestic Rabbit(100037717) potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
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Small Molecule - Allosteric Modulator
Small Molecule - Antagonist
Antibodies
Numéro du produit
Description
Espèces réactives
Application
Anti-Potassium Channel Kv1.1 Antibody, clone K36/15, clone K36/15, from mouse,
Espèces réactives
mouse, rat
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Potassium Channel Kv1.1 Antibody, Chemicon®, from rabbit,
Espèces réactives
mouse, rat
Application
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Monoclonal Anti-KCNA1 antibody produced in mouse, clone S36-15, 1 mg/mL, purified immunoglobulin,
Espèces réactives
mouse, rat
Application
immunocytochemistry
western blot
western blot
Anti-KCNA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-KCNA1 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
western blot
western blot
Small Molecule - Blocker
Numéro du produit
Description
Espèce(s)
Small Molecule - Inhibitor
Numéro du produit
Description
Espèce(s)