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KCNH2

potassium voltage-gated channel, subfamily H (eag-related), member 2

Sinónimos:
ERG1, HERG, HERG1, Kv11.1, LQT2, SQT1
Especie:
ID UniProtKB:
ID del gen:
  • Human(3757) Summary: This gene encodes a voltage-activated potassium channel belonging to the eag family. It shares sequence similarity with the Drosophila ether-a-go-go (eag) gene. Mutations in this gene can cause long QT syndrome type 2 (LQT2). Transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(16511) potassium voltage-gated channel, subfamily H (eag-related), member 2
  • Rat(117018) potassium voltage-gated channel, subfamily H (eag-related), member 2
  • Zebrafish(405763) potassium voltage-gated channel, subfamily H (eag-related), member 2
  • naked mole-rat(101711977) potassium voltage-gated channel, subfamily H (eag-related), member 2
  • domestic cat(101081621) potassium voltage-gated channel, subfamily H (eag-related), member 2
  • Horse(100064000) potassium voltage-gated channel, subfamily H (eag-related), member 2
  • Domestic Rabbit(100009242) potassium voltage-gated channel, subfamily H (eag-related), member 2
  • dog(403761) potassium voltage-gated channel, subfamily H (eag-related), member 2
  • domestic guinea pig(100135563) potassium voltage-gated channel, subfamily H (eag-related), member 2
  • cow(539971) potassium voltage-gated channel, subfamily H (eag-related), member 2

Custom & Knockdown Gene Products

Small Molecule - Antagonist

Número de producto
Descripción
Especie
Sotalol hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Sotalol hydrochloride, British Pharmacopoeia (BP) Reference Standard,
Especie
human
Glyburide, meets USP testing specifications,
Especie
rat, human
(±)-Sotalol hydrochloride, ≥98% (TLC), powder,
Especie
human
Glybenclamide, ≥99% (HPLC),
Especie
rat, human

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-Potassium Channel KV11.1 (HERG) Extracellular-FITC antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Reactividad de especies
human
Aplicación
flow cytometry
immunocytochemistry
Anti-Potassium Channel HERG Antibody, CT, Chemicon®, from rabbit,
Reactividad de especies
human
Aplicación
immunocytochemistry
immunoprecipitation (IP)

western blot
Anti-KCNH2 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Aplicación
western blot
Anti-Potassium Channel ERG1 Antibody, CT, Chemicon®, from rabbit,
Reactividad de especies
human, mouse, rat
Aplicación
immunocytochemistry
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-Potassium Channel Kv11.1 Extracellular antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Reactividad de especies
human
Aplicación
flow cytometry
immunocytochemistry

western blot

Small Molecule - Blocker

Número de producto
Descripción
Especie
Ibutilide hemifumarate salt, ≥98% (HPLC),
Especie
human
Dofetilide, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Dofetilide, ≥98% (HPLC),
Especie
human
Amiodarone hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Especie
human
Ibutilide fumarate, United States Pharmacopeia (USP) Reference Standard, monograph mol wt. 885.23 ([(C20H36N2O3S)2 . C4H4O4]),
Especie
human

Small Molecule - Inhibitor

Número de producto
Descripción
Especie
Loratadine, ≥98% (HPLC), powder,
Especie
rat, human
Terfenadine, ,
Especie
mouse, rat, human
Cocaine free base, ,
Especie
mouse, rat, human
Pimozide, ,
Especie
human, mouse, rat
Haloperidol, powder,
Especie
human, rat

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting human KCNH2,
Especie
human