1335610

Ibutilidfumarat

United States Pharmacopeia (USP) Reference Standard, monograph mol wt. 885.23 ([(C₂₀H₃₆N₂O₃S)₂ . C₄H₄O₄])

• Synonym(e): Ibutilid -hemifumarat (Salz)
• Empirische Formel (Hill-System): C₂₀H₃₆N₂O₃S · 0.5C₄H₄O₄
• CAS-Nummer: 122647-32-9
• Molekulargewicht: 442.61
• NACRES: NA.24
• PubChem Substance ID: 329750146
• UNSPSC Code: 41116107
• MDL number: MFCD01715410
• eCl@ss: 25140904

Eigenschaften

• grade: pharmaceutical primary standard
• agency: USP
• API family: ibutilide
• mol wt: monograph mol wt. 885.23
• manufacturer/tradename: USP
• application(s): pharmaceutical; pharmaceutical (small molecule); pharmaceutical
• format: neat
• storage temp.: 2-8°C
• SMILES string: OC(=O)\C=C\C(O)=O.CCCCCCCN(CC)CCCC(O)c1ccc(NS(C)(=O)=O)cc1.CCCCCCCN(CC)CCCC(O)c2ccc(NS(C)(=O)=O)cc2
• InChI: 1S/2C20H36N2O3S.C4H4O4/c2*1-4-6-7-8-9-16-22(5-2)17-10-11-20(23)18-12-14-19(15-13-18)21-26(3,24)25;5-3(6)1-2-4(7)8/h2*12-15,20-21,23H,4-11,16-17H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;;2-1+
• InChI key: PCIOHQNIRPWFMV-WXXKFALUSA-N
• Gene Information: human ... KCNH2(3757)

Beschreibung

General description

Find answers to frequently asked questions on USP products in USP FAQs.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Ibutilide fumarate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Biochem/physiol Actions

Ibutilide hemifumarate salt is considered a new generation "pure" Class III antiarrhythmic agent.

Ibutilide hemifumarate salt is considered a new generation "pure" Class III antiarrhythmic agent. Ibutilide binds to and alters the activity of hERG potassium channels, delayed inward rectifier potassium (IKr) channels and L-type (dihydropyridine sensitive) calcium channels.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Sicherheitshinweise

• Piktogramme: GHS08,GHS07
• Signalwort: Warning
• Gefahrencodes: H302,H361d
• Sicherheitshinweise: P202 - P264 - P270 - P280 - P301 + P312 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Repr. 2
• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable