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POLR2A

polymerase (RNA) II (DNA directed) polypeptide A, 220kDa

Sinónimos:
POLR2, POLRA, RPB1, RPBh1, RPO2, RPOL2, RpIILS, hRPB220, hsRPB1
Especie:
Human POLR2A (5430), Mouse Polr2a (20020), Rat Polr2a (363633), cow POLR2A (282312), naked mole-rat Polr2a (101725588), dog POLR2A (479483), Zebrafish polr2a (553347), sheep POLR2A (100144762), domestic cat POLR2A (101098500), domestic guinea pig Polr2a (100734232)
ID UniProtKB:
P24928, A6NN93, B9EH88
ID del gen:
  • Human(5430) Summary: This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. [provided by RefSeq, Jul 2008]
  • Mouse(20020) polymerase (RNA) II (DNA directed) polypeptide A
  • Rat(363633) polymerase (RNA) II (DNA directed) polypeptide A
  • cow(282312) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
  • naked mole-rat(101725588) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
  • dog(479483) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
  • Zebrafish(553347) polymerase (RNA) II (DNA directed) polypeptide A
  • sheep(100144762) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
  • domestic cat(101098500) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
  • domestic guinea pig(100734232) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa

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Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
MABE1975
Anti-p-RNA polymerase II CTD (Ser5) Antibody, clone CMA603, ,
Reactividad de especies
human
Aplicación
ChIP
ELISA
immunofluorescence
immunoprecipitation (IP)
western blot
05-952-I
Anti-RNA Polymerase II Antibody, CTD Antibody, clone 8WG16, clone 8WG16, from mouse,
Reactividad de especies
human, yeast
Aplicación
dot blot
immunoprecipitation (IP)
inhibition assay
western blot
MABE954
Anti-phospho RNA Pol II (Ser5), clone 1H4B6 Antibody, clone 1H4B6, from rat,
Reactividad de especies
canine, human, monkey, mouse, rat
Aplicación
ChIP
ELISA
immunocytochemistry
western blot
MABE953
Anti-phospho RNA Pol II (Ser2), clone 3E7C7 Antibody, clone 3E7C7, from rat,
Reactividad de especies
canine, human, monkey, mouse, rat
Aplicación
ChIP
ELISA
immunocytochemistry
western blot
ZMS1031
Anti-RNA polymerase II Antibody, clone CTD4H8 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, mouse, rat, yeast
Aplicación
flow cytometry
immunocytochemistry
immunohistochemistry
western blot

Proteins

Número de producto
Descripción
Especie
SRP2013
RNA Polymerase II, C-terminal human, recombinant, expressed in E. coli, ≥85% (SDS-PAGE),
Especie
human
SRP2120
RNA Polymerase II, C-terminal domain, GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE),
Especie
human

esiRNA

Número de producto
Descripción
Especie
EHU003451
MISSION® esiRNA, targeting human POLR2A,
Especie
human
EMU155061
MISSION® esiRNA, targeting mouse Polr2a,
Especie
mouse