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Merck

PPP2R1A

protein phosphatase 2, regulatory subunit A, alpha

Sinonimi:
PP2A-Aalpha, PP2AAALPHA, PR65A
Specie:
Human PPP2R1A (5518), Mouse Ppp2r1a (51792), Rat Ppp2r1a (117281), dog PPP2R1A (484335), Zebrafish ppp2r1a (406685), cow PPP2R1A (535321)
ID UniProtKB:
P30153, Q13773, Q6ICQ3, Q96DH3
ID gene:
  • Human(5518) Summary: This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes an alpha isoform of the constant regulatory subunit A. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010]
  • Mouse(51792) protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform
  • Rat(117281) protein phosphatase 2, regulatory subunit A, alpha
  • dog(484335) protein phosphatase 2, regulatory subunit A, alpha
  • Zebrafish(406685) protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform
  • cow(535321) protein phosphatase 2, regulatory subunit A, alpha

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Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
07-250
Anti-PP2A Antibody, A subunit, Upstate®, from rabbit,
Reattività con
xenopus, human, mouse, pig, rat
Applicazione
immunoprecipitation (IP)
western blot
SAB1401297
Monoclonal Anti-PPP2R1A antibody produced in mouse, clone 4E6, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
proximity ligation assay
western blot

Small Molecule - Inhibitor

Numero di prodotto
Descrizione
Specie
C7632
Cantharidin, ,
Specie
human

Proteins

Numero di prodotto
Descrizione
Specie
SRP0736
PP2A ALPHA/PPP2R1A Complex, Active, recombinant,
Specie
human

esiRNA

Numero di prodotto
Descrizione
Specie
EHU071351
MISSION® esiRNA, targeting human PPP2R1A,
Specie
human
EMU082181
MISSION® esiRNA, targeting mouse Ppp2r1a,
Specie
mouse