Passa al contenuto
Merck

TNFRSF11B

tumor necrosis factor receptor superfamily, member 11b

Sinonimi:
OCIF, OPG, TR1
Specie:
ID UniProtKB:
ID gene:
  • Human(4982) Summary: The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. [provided by RefSeq, Jul 2008]
  • Mouse(18383) tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)
  • Rat(25341) tumor necrosis factor receptor superfamily, member 11b
  • cow(523822) tumor necrosis factor receptor superfamily, member 11b
  • chicken(378803) tumor necrosis factor receptor superfamily, member 11b
  • Zebrafish(407674) tumor necrosis factor receptor superfamily, member 11b
  • dog(482025) tumor necrosis factor receptor superfamily, member 11b
  • Goat(100860896) tumor necrosis factor receptor superfamily, member 11b
  • Domestic Rabbit(100348133) tumor necrosis factor receptor superfamily, member 11b
  • domestic guinea pig(100715850) tumor necrosis factor receptor superfamily, member 11b
  • naked mole-rat(101709512) tumor necrosis factor receptor superfamily, member 11b
  • Horse(100065885) tumor necrosis factor receptor superfamily, member 11b
  • domestic cat(101096878) tumor necrosis factor receptor superfamily, member 11b

Custom & Knockdown Gene Products

ELISA

Numero di prodotto
Descrizione
Specie
Human Osteoprotegerin / TNFRSF11b ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Specie
human
Mouse Osteoprotegerin ELISA Kit, for serum, plasma, cell culture supernatant,
Specie
mouse
Porcine OPG ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Specie

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-Osteoprotegerin antibody produced in goat, affinity isolated antibody, lyophilized powder,
Reattività con
mouse
Applicazione
immunohistochemistry
neutralization

western blot
Anti-Tnfrsf11B Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
Anti-TNFRSF11B antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
western blot

Proteins

Numero di prodotto
Descrizione
Specie
Osteoprotegerin (OPG) human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Specie
human
Osteoprotegerin/Fc Chimera from mouse, >95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder,
Specie
mouse

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human TNFRSF11B,
Specie
human