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536709

PAMAM dendrimer, ethylenediamine core, generation 5.0 solution

5 wt. % in methanol

Synonym(s):

Poly(amidoamine)

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5 g
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$389.00

About This Item

Linear Formula:
[NH2(CH2)2NH2]:(G=5);dendri PAMAM(NH2)128
CAS Number:
Molecular Weight:
28824.81
UNSPSC Code:
12162002
NACRES:
NA.23
MDL number:

$389.00


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description

amino surface groups

Quality Segment

form

liquid

mol wt

generation 5.0

feature

core type ethylenediamine core (2-carbon core)

concentration

5 wt. % in methanol

no. Surface Groups

128

density

0.797 g/mL at 25 °C

storage temp.

2-8°C

General description

PAMAM dendrimers are water-soluble, non-immunogenic, and biocompatible symmetrical polymers. They possess a large quantity of modifiable terminal functional groups that can bind to various targeting or guest molecules. These terminal groups are used to covalently attach drugs, targeting ligands, or imaging agents for targeted delivery, controlled release, or imaging applications.

Application


  • Synthesis of beta-Cyclodextrin-Decorated Dendritic Compounds Based on EDTA Core: This study presents an alternative to the ethylenediamine core in PAMAM dendrimers, using an EDTA core instead, providing insights into modifications that affect the dendrimers properties (Gonzalez Mendez et al., 2022).

  • New Advances in General Biomedical Applications of PAMAM Dendrimers: Discusses the composition variations of PAMAM dendrimer cores, including ethylenediamine, and their implications on biomedical applications (Araujo et al., 2018).

  • Poly (amidoamine) Dendrimers: Covalent and Supramolecular Synthesis: This paper reviews various synthetic strategies for PAMAM dendrimers, emphasizing the role of the ethylenediamine core in their structural formation (Lyu et al., 2019).

  • Modified Carboxyl-Terminated PAMAM Dendrimers as a Cytocompatible Nano Based Drug Delivery System: Examines the biocompatibility and drug delivery efficiency of modified PAMAM dendrimers, highlighting the cores critical role (Vu et al., 2019).

  • Use of Polyaminoamide Dendrimers Starting from Different Core-Initial Molecules for Inhibition of Silica Scale: This study explores the use of ethylenediamine-core PAMAM dendrimers in industrial applications, particularly for silica scale inhibition (Sun et al., 2021).

Physical form

Contains 128 surface primary amino groups.

Legal Information

Manufactured by Dendritech®, Inc.
Dendritech is a registered trademark of Dendritech, Inc.

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This Item
536717412368412422
description

5 wt. % in methanol

description

5 wt. % in methanol

description

ethylenediamine core, generation 0.0 solution, 20 wt. % in methanol

description

20 wt. % in methanol

form

liquid

form

liquid

form

liquid

form

liquid

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

density

0.797 g/mL at 25 °C

density

0.806 g/mL at 25 °C

density

0.854 g/mL at 25 °C

density

0.863 g/mL at 25 °C

Quality Level

100

Quality Level

100

Quality Level

200

Quality Level

100

description

amino surface groups

description

amino surface groups

description

amino surface groups

description

amino surface groups

feature

core type ethylenediamine core (2-carbon core)

feature

core type ethylenediamine core (2-carbon core)

feature

core type ethylenediamine core (2-carbon core)

feature

core type ethylenediamine core (2-carbon core)


signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

49.5 °F - closed cup - Methanol

flash_point_c

9.7 °C - closed cup - Methanol



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Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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