P2645
Protein Kinase A Catalytic Subunit from bovine heart
≥9 units/μg protein (cyclic-AMP is not required for this activity), lyophilized (white powder to sticky mass to hard pellet)
Synonyme(s) :
PKA
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| À vous/Référence | Disponibilité | Prix |
|---|---|---|
Veuillez contacter notre Service Clients pour connaître la disponibilité de ce produit. | 233,00 € |
A propos de cet article
UNSPSC Code:
12352204
eCl@ss:
32160410
NACRES:
NA.32
MDL number:
Specific activity:
≥9 units/μg protein (cyclic-AMP is not required for this activity)
233,00 €
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lyophilized (white powder to sticky mass to hard pellet)
Quality Segment
specific activity
≥9 units/μg protein (cyclic-AMP is not required for this activity)
mol wt
40,862 Da
storage temp.
−20°C
General description
Application
Protein Kinase A (PKA) Catalytic Subunit from bovine heart has been used-
Biochem/physiol Actions
Protein Kinase A (PKA) controls the transduction of Hedgehog signaling and participates in proliferation and fate specification. It phosphorylates several neurotransmitter receptors, transcription factors and constituents of various intracellular signaling pathways.
Protein Kinase A catalyzes the transfer of terminal phosphate from ATP to threonine or serine residues present on various proteins. This protein is inactive in the absence of cAMP, where the catalytic and regulatory subunits are bound together. The regulatory subunit, in the presence of cAMP, binds to cAMP and releases the catalytic subunit.[7]
Packaging
Package size based on phosphorylating units
Physical form
Lyophilized powder with sucrose and phosphate buffer salts as stabilizer.
Preparation Note
Prepared from protein kinase A (P 5511)
Other Notes
Phosphorylating Activity: One unit will transfer 1.0 picomole phosphate from ATP to hydrolyzed and partially dephosphorylated casein per minute at pH 6.5 at 30°C, determined by measuring the production of ADP.
Disclaimer
Please note that the pack size has been changed to align with the unit definition, while the number of phosphorylating units remain the same as before.
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Cet article | |||
|---|---|---|---|
| specific activity ≥9 units/μg protein (cyclic-AMP is not required for this activity) | specific activity ≥0.8 units/μg protein | specific activity >1000 units/mg protein | specific activity ≥20,000 units/μg protein |
| form lyophilized (white powder to sticky mass to hard pellet) | form lyophilized powder | form buffered aqueous glycerol solution | form liquid |
| storage temp. −20°C | storage temp. −20°C | storage temp. −70°C | storage temp. −70°C |
| mol wt 40,862 Da | mol wt - | mol wt 43.5 kDa | mol wt - |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 100 |
Classe de stockage
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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