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16005

Brij® L23

main component: tricosaethylene glycol dodecyl ether

Synonym(s):

Brij 35, C12E23, Polyoxyethylene (23) lauryl ether

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Pack SizeSKUAvailabilityPrice
250 g
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€ 42,20
1 kg
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€ 126,00

About This Item

CAS Number:
9002-92-0
NACRES:
NA.21
PubChem Substance ID:
57647536
UNSPSC Code:
12161900
MDL number:
MFCD00080891

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Quality Level

200

description

non-ionic

form

pellets

CMC

91 μM

mp

39-43 °C

HLB value

16.9

solubility

H2O: 40 mg/mL at 20 °C, clear to slightly hazy, colorless

cation traces

Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤500 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Na: ≤500 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg

functional group

ether, hydroxyl

SMILES string

CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO

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Show Differences

1 of 1

This Item
B41842359898.01962
Brij® L23 main component: tricosaethylene glycol dodecyl ether

Sigma-Aldrich

16005

Brij® L23

Brij® L23 solution 30 % (w/v) in H2O

Sigma-Aldrich

B4184

Brij® L23 solution

Brij® L4 average Mn ~362

Sigma-Aldrich

235989

Brij® L4

Brij® 35 for synthesis

Sigma-Aldrich

8.01962

Brij® 35

form

pellets

form

liquid

form

solid or liquid

form

solid

description

non-ionic

description

non-ionic

description

non-ionic

description

-

mp

39-43 °C

mp

-

mp

48 °C

mp

-

CMC

91 μM

CMC

91 μM

CMC

-

CMC

-

solubility

H2O: 40 mg/mL at 20 °C, clear to slightly hazy, colorless

solubility

water: soluble

solubility

water: insoluble

solubility

-

cation traces

Ca: ≤10 mg/kg, Co: ≤5 mg/kg, Cu: ≤5 mg/kg, K: ≤500 mg/kg, Mn: ≤5 mg/kg, Ni: ≤5 mg/kg, Zn: ≤5 mg/kg, Cd: ≤5 mg/kg, Fe: ≤5 mg/kg, Na: ≤500 mg/kg, Cr: ≤5 mg/kg, Pb: ≤5 mg/kg, Mg: ≤5 mg/kg

cation traces

-

cation traces

-

cation traces

-

Application

Brij® L23 is a detergent used for measuring the concentration of carbon black in lung tissues.[1] It has also been used for selective and rapid solubilization of microbial membrane aldehyde dehydrogenase.[2] Additionally, the product has also been used for assessing whether acrolein could lead to pro-enzyme activation by using gelatin zymography.[3]

Biochem/physiol Actions

Brij® L23 also referred to as Brij 35 or Polyoxyethylene (23) lauryl ether is a non-ionic detergent that lowers the non-specific protein adsorption and reduces electroosmotic pumping drastically.[4] This allows the pH to be varied without adversely affecting the flow rate. It also used as a nonionic surfactant that decreases the absorbance of the blank, inhibits turbidity as well as provides linearity.[5]

Other Notes

Non-ionic polyoxyethylene ether.[6] Used for selective and rapid solubilization of microbial membrane aldehyde dehydrogenase.[2]

Legal Information

Brij is a registered trademark of Croda International PLC

Storage Class

11 - Combustible Solids

wgk

WGK 2

ppe

dust mask type N95 (US), Eyeshields, Gloves

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCP3524
BCCP1717
BCCN9139
BCCN2783
BCCN0695

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J K Towns et al.
Analytical chemistry, 63(11), 1126-1132 (1991-06-01)
Capillary zone electrophoretic separations of proteins have been achieved by using nonionic surfactant coated capillaries. Capillaries were prepared by derivatization of the silica surface with octadecylsilane followed by the deposition of a layer of nonionic surfactant from an aqueous solution
Cheol-Hong Lim et al.
Environmental health and toxicology, 28, e2013014-e2013014 (2013-12-05)
This study was conducted to determine whether nano-sized carbon black exposure results in greater damage in high fat diet-induced overweight rats than normal weight ones and to identify the possible causes of any differences. Two groups of Sprague-Dawley rats allocated
B T Dumas et al.
Clinica chimica acta; international journal of clinical chemistry, 258(1), 21-30 (1997-02-03)
A rapid and reliable method for measuring serum albumin employing bromcresol green is described. The addition of albumin to a solution of bromcresol green in a 0.075 M succinate buffer pH 4.20 results in an increase in absorbance at 628
Hitesh S Deshmukh et al.
American journal of respiratory cell and molecular biology, 38(4), 446-454 (2007-11-17)
Chronic obstructive pulmonary disease (COPD), a global public health problem, is characterized by progressive difficulty in breathing, with increased mucin production, especially in the small airways. Acrolein, a constituent of cigarette smoke and an endogenous mediator of oxidative stress, increases
Johanna Zemva et al.
Redox biology, 13, 674-686 (2017-08-22)
Energy production is inevitably linked to the generation of toxic metabolites, such as reactive oxygen and carbonyl species, known as major contributors to ageing and degenerative diseases. It remains unclear how cells can adapt to elevated energy flux accompanied by
View All Related Papers

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Global Trade Item Number

SKUGTIN
16005-25KG-R04061832489292
16005-1KG-F04061838744944
16005-6X1KG-R04061832489308
16005-250G-F04061838744968
16005-1KG-R04061838744951

Questions

1–3 of 3 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  3. What is the Department of Transportation shipping information for this product?

    1 answer

    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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