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30320

Cytidine 5′-triphosphate disodium salt hydrate

≥90.0% (HPLC), solid

Synonym(s):

5-CTP-Na2, CTP

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100 mg
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$161.00
500 mg
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$554.00

About This Item

Empirical Formula (Hill Notation):
C9H14N3Na2O14P3 · xH2O
CAS Number:
652154-13-7
Molecular Weight:
527.12 (anhydrous basis)
NACRES:
NA.51
PubChem Substance ID:
57648425
UNSPSC Code:
41106305
MDL number:
MFCD00150809
Beilstein/REAXYS Number:
3582735
Assay:
≥90.0% (HPLC)
Form:
solid
Solubility:
H2O: 50 mg/mL, clear, colorless
Storage temp.:
−20°C

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Product Name

Cytidine 5′-triphosphate disodium salt hydrate, ≥90.0% (HPLC)

Quality Level

100

assay

≥90.0% (HPLC)

form

solid

impurities

≤12% water

solubility

H2O: 50 mg/mL, clear, colorless

shipped in

wet ice

storage temp.

−20°C

SMILES string

O.[Na+].[Na+].NC1=NC(=O)N(C=C1)[C@@H]2O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]2O

InChI

1S/C9H16N3O14P3.2Na.H2O/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18;;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H2,10,11,15)(H2,16,17,18);;;1H2/q;2*+1;/p-2/t4-,6-,7-,8-;;;/m1.../s1

InChI key

IJMSOWKYYIROGP-LLWADOMFSA-L

Application

Cytidine 5′-triphosphate disodium salt hydrate has been used:
  • in the oligonucleotide synthesis for silver nanoclusters interaction studies
  • as an anion source for fluorescence emission and titration curve-analysis of hypocrellin A-zinc(II) complex
  • in fluorescence emission experiments of copper(II)–2,6-bis(2-benzimidazolyl)pyridine complex

Cytidine 5γ-triphosphate (CTP) is used to synthesize RNA by various RNA polymerases. Cytidine 5γ-triphosphate (CTP) is a substrate for CMP-neuNAc synthetase(s) which produce CMP-neuNAc used in sialylation reactions. As a substrate of CTP:phosphocholine cytidylyltransferase(s) (CT), CTP supports the formation of phosphatidylcholine via the formation of CDP-choline.

Biochem/physiol Actions

Cytidine 5′-triphosphate (CTP) is essential for the synthesis of DNA and is a mediator of many physiological processes in living systems. It is crucial for the dolichol phosphorylation, cholesterol transport and is involved in the allosteric regulation of aspartate transcarbamylase. It is also used in the treatment of disease related brain.

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This Item
30290C8552C1506
Cytidine 5′-triphosphate disodium salt hydrate ≥90.0% (HPLC)

Sigma-Aldrich

30320

Cytidine 5′-triphosphate disodium salt hydrate

Cytidine 5′-diphosphocholine sodium salt hydrate ≥99.0% (HPLC)

Sigma-Aldrich

30290

Cytidine 5′-diphosphocholine sodium salt hydrate

Cytidine 5′-triphosphate disodium solution HPLC purified, aqueous solution for RNA polymerase transcription

Sigma-Aldrich

C8552

Cytidine 5′-triphosphate disodium solution

Cytidine 5′-triphosphate disodium salt ≥95%

Sigma-Aldrich

C1506

Cytidine 5′-triphosphate disodium salt

Quality Level

100

Quality Level

100

Quality Level

300

Quality Level

200

form

solid

form

powder

form

liquid

form

powder

assay

≥90.0% (HPLC)

assay

≥99.0% (HPLC)

assay

-

assay

≥95%

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

solubility

H2O: 50 mg/mL, clear, colorless

solubility

-

solubility

-

solubility

-

shipped in

wet ice

shipped in

-

shipped in

dry ice

shipped in

-

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

235.4 °F - closed cup

flash_point_c

113 °C - closed cup

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM2047
BCCH6860
BCCD4350
BCBV6021
BCBS5960V

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Melissa A MacKinnon et al.
The Journal of biological chemistry, 284(11), 7376-7384 (2009-01-15)
Phosphatidylcholine is the major phospholipid in eukaryotic cells. There are two main pathways for the synthesis of phosphatidylcholine: the CDP-choline pathway present in all eukaryotes and the phosphatidylethanolamine methylation pathway present in mammalian hepatocytes and some single celled eukaryotes, including
J Vionnet et al.
Glycobiology, 9(5), 481-487 (1999-04-20)
CMP-beta-N-acetylneuraminic acid (CMP-neuNAc) is the substrate for the sialylation of glycoconjugates by sialyltransferases in microbes and higher eukaryotes. CMP-neuNAc synthetase catalyzes the formation of this substrate, CMP-neuNAc, from CTP and neuNAc. In this report we describe the purification of CMP-neuNAc
U Edwards et al.
FEMS microbiology letters, 75(2-3), 161-166 (1992-09-15)
The CMP-N-acetylneuraminic acid (CMP-NeuNAc) synthetase gene of Neisseria meningitidis group B is located on a 2.3-kb EcoRI fragment within the cps gene cluster. Nucleotide sequence determination of the gene encoding the CMP-NeuNAc synthetase revealed a 515-bp open reading frame that
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Global Trade Item Number

SKUGTIN
30320-100MG04061826666272
30320-500MG04061833488874

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