C5241
Cinnamycin
From Streptomyces cinnamoneus, ≥95% (HPLC), peptide antibiotic, solid
Synonym(s):
Lanthiopeptin, NSC-71936, Ro 09-0198
Select a Size
| Size/SKU | Availability | Price |
|---|---|---|
1 mg | Check Cart for Availability | $734.00 |
About This Item
Product Name
Cinnamycin, from Streptomyces cinnamoneus, ≥95% (HPLC)
biological source
Streptomyces cinnamoneus
Quality Segment
assay
≥95% (HPLC)
form
solid
solubility
DMSO: 10 mg/mL, acetonitrile: water (1:1): 5 mg/mL (requires heating)
antibiotic activity spectrum
fungi
mode of action
cell membrane | interferes
storage temp.
2-8°C
SMILES string
S1[C@@H](C2NC(=O)[C@@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@H]3NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H]5NC(=O)[C@@H](NC(=O)[C@H]7N(CCC7)C(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](C1)N)CCCN\C(=N/[H])\N)CCC(=O)N)CS
InChI
1S/C89H125N25O25S3/c1-43(2)66-84(133)109-59-41-140-40-58-79(128)108-60-42-142-45(4)68(86(135)105-55(75(124)110-66)34-48-22-12-7-13-23-48)111-76(125)54(33-47-20-10-6-11-21-47)104-82(131)61-26-17-31-114(61)65(118)38-98-72(121)53(32-46-18-8-5-9-19-46)103-78(127)57(106-80(60)129)36-95-29-15-14-24-52(87(136)137)102-85(134)67(112-77(126)56(35-63(92)116)99-64(117)37-97-83(132)69(113-81(59)130)70(119)88(138)139)44(3)141-39-49(90)71(120)100-50(25-16-30-96-89(93)94)73(122)101-51(74(123)107-58)27-28-62(91)115/h5-13,18-23,43-45,49-61,66-70,95,119H,14-17,24-42,90H2,1-4H3,(H2,91,115)(H2,92,116)(H,97,132)(H,98,121)(H,99,117)(H,100,120)(H,101,122)(H,102,134)(H,103,127)(H,104,131)(H,105,135)(H,106,129)(H,107,123)(H,108,128)(H,109,133)(H,110,124)(H,111,125)(H,112,126)(H,113,130)(H,136,137)(H,138,139)(H4,93,94,96)/t44-,45?,49+,50+,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,66+,67?,68+,69+,70-/m1/s1
InChI key
QJDWKBINWOWJNZ-IDGBIKHQSA-N
General description
Application
Biochem/physiol Actions
Cinnamycin, like other lantibiotics, was also reported to inhibit phospholipase A2 (PLA2). It was suggested as an alternative treatment for atherosclerosis through its ability to inhibit PLA2 by binding to its substrate PE. Moreover, Cinnamycin was found to inhibit Herpes simplex virus (HSV-1) activity.
1 of 1
This Item | |||
|---|---|---|---|
| description from Streptomyces cinnamoneus, ≥95% (HPLC) | description Pharmaceutical Secondary Standard; Certified Reference Material | description The Akt Inhibitor VI, Akt-in controls the biological activity of Akt. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. | description The 28-amino acid n-octanoylated (at ser3) natural peptidyl ligand for the growth hormone secretagogue receptor 1a (GHSR1a). |
| form solid | form - | form lyophilized solid | form solid |
| assay ≥95% (HPLC) | assay - | assay ≥95% (HPLC) | assay ≥95% (HPLC) |
| Quality Level 200 | Quality Level 300 | Quality Level 100 | Quality Level 100 |
| storage temp. 2-8°C | storage temp. -10 to -25°C | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility acetonitrile: water (1:1): 5 mg/mL (requires heating), DMSO: 10 mg/mL | solubility - | solubility water: 1 mg/mL | solubility water: 1 mg/mL |
| antibiotic activity spectrum fungi | antibiotic activity spectrum - | antibiotic activity spectrum - | antibiotic activity spectrum - |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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