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A3286

N-Acetyl-D-glucosamine

BioReagent, suitable for cell culture

Synonym(s):

2-Acetamido-2-deoxy-D-glucose, D-GlcNAc

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5 g
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$50.30
25 g
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$119.00
100 g
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$403.00

About This Item

Empirical Formula (Hill Notation):
C8H15NO6
CAS Number:
7512-17-6
Molecular Weight:
221.21
UNSPSC Code:
12352201
NACRES:
NA.75
PubChem Substance ID:
24890757
EC Number:
231-368-2
Beilstein/REAXYS Number:
1727589
MDL number:
MFCD00061615

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product line

BioReagent

Quality Level

200

assay

≥95% (HPLC)

form

powder

technique(s)

cell culture | mammalian: suitable

mp

211 °C (dec.) (lit.)

application(s)

advanced drug delivery

storage temp.

−20°C

SMILES string

CC(=O)N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O

InChI

1S/C8H15NO6/c1-3(11)9-5-7(13)6(12)4(2-10)15-8(5)14/h4-8,10,12-14H,2H2,1H3,(H,9,11)/t4-,5-,6-,7-,8?/m1/s1

InChI key

OVRNDRQMDRJTHS-RTRLPJTCSA-N

General description

N-Acetylglucosamine (GlcNAc), a derivative of glucose is a monosaccharide. It is a white powder and is mildly sweet. It melts at 221°C. GlcNAc is 25% soluble in water. It is present in bromelain, ricin agglutinin and abrus agglutinin, in plants. In humans, it is present in tissue plasminogen activator, growth factors and hormones.[1]

Application

N-Acetyl-D-glucosamine addition has been used:
  • as a substrate to develop dot-blots
  • as a substrate to reveal alkaline phosphatase in the immunohistochemical analysis[1]
  • to detect specific immune complexes in western blot analysis

Biochem/physiol Actions

N-Acetylglucosamine (GlcNAc) oligomer may have the ability to initiate factors for canine polymorphonuclear cells (PMN) in vivo. It possesses wound healing and chemotactic activity. GlcNAc and its derivatives are usually employed in preparing dietary supplements and also used in therapeutic development.[1]

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This Item
A41061079A8625
N-Acetyl-D-glucosamine BioReagent, suitable for cell culture

Sigma-Aldrich

A3286

N-Acetyl-D-glucosamine

N-Acetyl-D-glucosamine ≥95% (HPLC)

Sigma-Aldrich

A4106

N-Acetyl-D-glucosamine

N-Acetyl-D-glucosamine An acceptor substrate for galactosyltransferases. Inhibits the lectin WGA and β-N-acetylhexosaminidase (Ki = 430 µM). When added to a medium, it improves the recovery of Haemophilus influenza from sputum.

Millipore

1079

N-Acetyl-D-glucosamine

N-Acetyl-D-glucosamine ≥99% (HPLC)

Sigma-Aldrich

A8625

N-Acetyl-D-glucosamine

technique(s)

cell culture | mammalian: suitable

technique(s)

-

technique(s)

-

technique(s)

HPLC: suitable

assay

≥95% (HPLC)

assay

≥95% (HPLC)

assay

≥98% (HPLC)

assay

≥99% (HPLC)

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

200

form

powder

form

powder

form

powder

form

powder

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

−20°C

mp

211 °C (dec.) (lit.)

mp

211 °C (dec.) (lit.)

mp

-

mp

211 °C (dec.) (lit.)

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000563931
0000563926
0000560694
0000545290
0000545291

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Glucose metabolism and hexosamine pathway regulate oncogene-induced senescence
Gitenay D, et al.
Cell Death & Disease, 5(2), e1089-e1089 (2014)
Cumulus expansion, nuclear maturation and connexin 43, cyclooxygenase-2 and FSH receptor mRNA expression in equine cumulus-oocyte complexes cultured in vitro in the presence of FSH and precursors for hyaluronic acid synthesis
Dell'Aquila M E, et al.
Reproductive Biology and Endocrinology, 2(1), 44-44 (2004)
Glycoprofiling effects of media additives on IgG produced by CHO cells in fed-batch bioreactors
Kildegaard H F, et al.
Biotechnology and Bioengineering, 113(2), 359-366 (2016)
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Global Trade Item Number

SKUGTIN
A3286-5G04061833360620
A3286-100G04061833360613
A3286-25G04061835522552

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