This substance is synthetic organic. The product has been offered previously before 2023. See below for an example of the Certificate of Origin.
https://www.sigmaaldrich.com/coo/undefined/A5752/SHBL7005
A5752
Adrenochrome
>95% purity (HPLC), powder
Synonym(s):
3-Hydroxy-1-methyl-5,6-indolinedione
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 25 mg | Estimated to ship onMay 07, 2026fromMILWAUKEE | $76.80 | |
| 250 mg | Estimated to ship onMay 07, 2026fromMILWAUKEE | $480.00 |
About This Item
Empirical Formula (Hill Notation):
C9H9NO3
CAS Number:
Molecular Weight:
179.17
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
EC Number:
200-192-8
MDL number:
Product Name
Adrenochrome, ≥95% (HPLC)
Quality Level
assay
≥95% (HPLC)
form
powder
color
red to brown
εmax
3-4.5 at 485-490 nm in water, 9.0-10.5 at 299-304 nm in water
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
−20°C
SMILES string
CN1CC(O)C2=CC(=O)C(=O)C=C12
InChI
1S/C9H9NO3/c1-10-4-9(13)5-2-7(11)8(12)3-6(5)10/h2-3,9,13H,4H2,1H3
Related Categories
1 of 1
This Item | |||
|---|---|---|---|
| color red to brown | color - | color pink to very dark red | color - |
| application(s) diagnostic assay manufacturing | application(s) diagnostic assay manufacturing | application(s) diagnostic assay manufacturing | application(s) diagnostic assay manufacturing |
| form powder | form powder | form powder | form powder |
| assay ≥95% (HPLC) | assay - | assay ≥95% | assay >99% (TLC) |
| Quality Level 200 | Quality Level 200 | Quality Level 100 | Quality Level 200 |
| storage temp. −20°C | storage temp. room temp | storage temp. −20°C | storage temp. −20°C |
Application
Adrenochrome has been used to study the effect of adrenochrome on coronary artery constriction in the rat heart.
Biochem/physiol Actions
Adrenochrome is an oxidation product of adrenaline. It has been implicated in cardiotoxicity. It is a short-lived cytotoxic molecule and is part of the leukocyte response used to kill bacteria. Adrenochrome is also suggested to exhibit psychotomimetic effects. It is used to determine superoxide dismutase activity.
related product
Product No.
Description
Pricing
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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The adrenochrome hypothesis of schizophrenia revisited.
Smythies J
Neurotoxicity Research, 4, 147-147 (2002)
Vera Marisa Costa et al.
Chemical research in toxicology, 20(8), 1183-1191 (2007-07-17)
High concentrations of circulating biogenic catecholamines often exist during the course of several cardiovascular disorders. Additionally, coronary dysfunctions are prominent and frequently related to the ischemic and reperfusion phenomenon (I/R) in the heart, which leads to the release of large
The oxidative metabolism of catecholamines in the brain: a review.
Smythies J and Galzigna L
Biochimica et Biophysica Acta, 1380, 159-159 (1998)
Viviana S Fluxá et al.
Nature protocols, 3(8), 1270-1277 (2008-08-21)
The adrenaline test for enzymes is a colorimetric enzyme assay based on the quantification of periodate-sensitive reaction products such as 1,2-diols and 1,2-aminoalcohols by back-titration of the oxidant with adrenaline to produce adrenochrome as an easily detectable red product. The
John A Mills
History of psychology, 13(2), 178-195 (2010-06-11)
Working in a psychiatrically innovative environment created by the Government of Saskatchewan, Canada, Abram Hoffer and Humphry F. Osmond enunciated the adrenochrome hypothesis for the biogenesis of schizophrenia in 1952, slightly later proposing and, apparently, demonstrating, in a double-blind study
Global Trade Item Number
| SKU | GTIN |
|---|---|
| A5752-25MG | 04061832339986 |
| A5752-250MG | 04061832339979 |
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Is this substance synthetic or naturally derived? Some download able Data on this product is dated 1/16/2023. Is this a relatively new substance?
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