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A5752

Sigma-Aldrich

Adrenochrome

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Synonym(s):
3-Hydroxy-1-methyl-5,6-indolinedione
Empirical Formula (Hill Notation):
C9H9NO3
CAS Number:
Molecular Weight:
179.17
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.47

assay

>95% (HPLC)

Quality Level

form

powder

εmax

3-4.5 at 485-490 nm in water
9.0-10.5 at 299-304 nm in water

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

−20°C

SMILES string

CN1CC(O)C2=CC(=O)C(=O)C=C12

InChI

1S/C9H9NO3/c1-10-4-9(13)5-2-7(11)8(12)3-6(5)10/h2-3,9,13H,4H2,1H3

InChI key

RPHLQSHHTJORHI-UHFFFAOYSA-N

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1 of 4

This Item
214515N5625N2125
Adrenochrome

A5752

Adrenochrome

Chromotrope FB Dye content 50 %

214515

Chromotrope FB

Naphthol AS phosphate >99% (TLC), histochemical substrate

N5625

Naphthol AS phosphate

Naphthol AS-BI phosphate Technical grade, ≥98% (HPLC)

N2125

Naphthol AS-BI phosphate

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

assay

>95% (HPLC)

assay

-

assay

>99% (TLC)

assay

98% (HPLC)

εmax

3-4.5 at 485-490 nm in water, 9.0-10.5 at 299-304 nm in water

εmax

-

εmax

-

εmax

-

storage temp.

−20°C

storage temp.

room temp

storage temp.

−20°C

storage temp.

−20°C

application

Adrenochrome has been used to study the effect of adrenochrome on coronary artery constriction in the rat heart.

Biochem/physiol Actions

Adrenochrome is an oxidation product of adrenaline. It has been implicated in cardiotoxicity. It is a short-lived cytotoxic molecule and is part of the leukocyte response used to kill bacteria. Adrenochrome is also suggested to exhibit psychotomimetic effects. It is used to determine superoxide dismutase activity.

related product

Product No.
Description
Pricing

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Customers Also Viewed

Slide 1 of 8

1 of 8

Ventricular dysfunction and necrosis produced by adrenochrome metabolite of epinephrine: relation to pathogenesis of catecholamine cardiomyopathy.
Yates JC, et al.
American Heart Journal, 102, 210-210 (1981)
Zhimin Tao et al.
Langmuir : the ACS journal of surfaces and colloids, 25(17), 10183-10188 (2009-05-27)
We have measured the influence of mesoporous silica (MCM-41 and SBA-15) nanoparticles and dense silica nanoparticles on epinephrine oxidation, a pH-dependent reaction, whose rate is small in acidic or neutral solutions but much greater at higher pH. The reaction was
Towards an adrenaline biosensor based on substrate recycling amplification in combination with an enzyme logic gate.
Molinnus D, et al.
Sensors and Actuators B, Chemical, 237, 190-195 (2016)
John A Mills
History of psychology, 13(2), 178-195 (2010-06-11)
Working in a psychiatrically innovative environment created by the Government of Saskatchewan, Canada, Abram Hoffer and Humphry F. Osmond enunciated the adrenochrome hypothesis for the biogenesis of schizophrenia in 1952, slightly later proposing and, apparently, demonstrating, in a double-blind study
Effect of Bacillus coagulans and B. firmus incorporated probiotic diet on Superoxide dismutase activity and catalase activity in Penaeus monodon.
Raghu P, et al.
World Scientific News, 44, 224-224 (2016)

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