C3660
Complement C9 from human serum
≥150,000 C9H50 units/mg (using C9 deficient serum)
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| Size/SKU | Availability | Price |
|---|---|---|
0.1 mg | Check Cart for Availability | $360.00 |
About This Item
Form:
solution
Assay:
≥85% (SDS-GE)
Biological source:
human
Application
Complement C9 from human serum is an essential part of the terminal complement system. It has been a topic in cancer research, where extracellular phosphorylation by ecto-PK of K562 cells on serine residues may serve as a protective mechanism against complement in tumor cells. Additionally, it can be used as a biomarker (in fucosylated form) for squamous cell lung cancer, as patients tend to show elevated levels of C9 protein.
Biochem/physiol Actions
Physical form
Supplied as a solution in phosphate buffered saline, pH 7.2.
Analysis Note
Functionally pure by a sensitive hemolytic assay using deficient sera.
Other Notes
View more information on the complement pathway at www.sigma-aldrich.com/enzymeexplorer
Disclaimer
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
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This Item | |||
|---|---|---|---|
| description ≥150,000 C9H50 units/mg (using C9 deficient serum) | description ≥3000 C3H50 units/mg (using C3 deficient serum) | description ≥85% (SDS-PAGE), ≥150,000 C7H50 units/mg protein | description suitable for radioiodination, RIA, ≥85% (SDS-PAGE), ≥125,000 C8H50 units/mg protein (using C8 deficient serum) |
| assay ≥85% (SDS-GE) | assay ≥85% (SDS-GE) | assay ≥85% (SDS-PAGE) | assay ≥85% (SDS-PAGE) |
| biological source human | biological source human | biological source human serum | biological source human |
| form solution | form solution | form solution | form solution |
| UniProt accession no. | UniProt accession no. | UniProt accession no. | UniProt accession no. |
| shipped in dry ice | shipped in dry ice | shipped in dry ice | shipped in dry ice |
| storage temp. −70°C | storage temp. −70°C | storage temp. −70°C | storage temp. −70°C |
Storage Class
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
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