D1916
5,6-Dichlorobenzimidazole 1-β-D-ribofuranoside
≥98% (HPLC), powder, RNA synthesis inhibitor
Synonym(s):
5,6-Dichloro-1-β-D-ribofuranosylbenzimidazole, 5,6-Dichlorobenzimidazole riboside, DRB
Select a Size
| Size/SKU | Availability | Price |
|---|---|---|
10 mg | Available to ship TODAYfromMILWAUKEE | $73.00 |
50 mg | Available to ship TODAYfromMILWAUKEE | $206.00 |
About This Item
Product Name
5,6-Dichlorobenzimidazole 1-β-D-ribofuranoside,
Quality Segment
form
powder
storage temp.
−20°C
SMILES string
OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3cc(Cl)c(Cl)cc23
InChI
1S/C12H12Cl2N2O4/c13-5-1-7-8(2-6(5)14)16(4-15-7)12-11(19)10(18)9(3-17)20-12/h1-2,4,9-12,17-19H,3H2/t9-,10-,11-,12-/m1/s1
InChI key
XHSQDZXAVJRBMX-DDHJBXDOSA-N
Gene Information
human ... CSNK2A1(1457), CSNK2B(1460)
Application
- as an inhibitor of RNA polymerase II in mouse melanoma cells
- for the inhibition of cyclin D1 mRNA synthesis in human prostate epithelial cell lines
- in the inhibition of interleukin-2 gene transcription in Jurkat cells
Biochem/physiol Actions
Features and Benefits
1 of 1
This Item | |||
|---|---|---|---|
| description - | description A potent, ATP-competitive, and specific inhibitor of casein kinase II (IC50 = 6 µM). | description ≥98% (HPLC) | description The β-Catenin/Tcf Inhibitor II, PKF118-310 controls the biological activity of β-Catenin/Tcf. This small molecule/inhibitor is primarily used for Cancer applications. |
| form powder | form solid | form powder | form solid |
| Quality Level 200 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| storage temp. −20°C | storage temp. 10-30°C | storage temp. 2-8°C | storage temp. 2-8°C |
| Gene Information human ... CSNK2A1(1457), CSNK2B(1460) | Gene Information - | Gene Information - | Gene Information - |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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