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Monoclonal Anti-Fibrinogen antibody produced in mouse

Name: Monoclonal Anti-Fibrinogen antibody produced in mouse
Brand: SIGMA
Price: 553.35 USD
Availability: InStock

clone FG-21, ascites fluid

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Size/SKU	Availability	Price
0.2 mL	Estimated to ship onMay 26, 2026fromMILWAUKEE	$651.00 $553.35

About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD00162408

Conjugate:

unconjugated

Clone:

FG-21, monoclonal

Application:

ELISA (i)

Citations:

$553.35

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Properties

biological source

mouse

Quality Segment

200

conjugate

unconjugated

antibody form

ascites fluid

antibody product type

primary antibodies

clone

FG-21, monoclonal

contains

15 mM sodium azide

species reactivity

human, baboon

technique(s)

indirect ELISA: 1:4,000

isotype

IgG2a

UniProt accession no.

P02671

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... FGA(2243), FGB(2244), FGG(2266)

Description

General description

Fibrinogen, is a thrombin-coagulable soluble plasma 340kDa glycoprotein, composed of paired sets of three subunits i.e. α, β, γ. Among three subunits, β and γ subunits contain one N-glycosylation site, which is occupied by a biantennary N-glycan. It contains three pairs of disulfide bonded chains called α, β, γ which further folded into four structural domains: the D, E, connector and the COOH-terminal region of the Aα chain.

Monoclonal Anti-Fibrinogen (mouse IgG2a isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse.

Immunogen

purified haptoglobin from pooled human plasma containing the three major haptotypes.

Application

Monoclonal Anti-Fibrinogen antibody produced in mouse has been used in:

enzyme linked immunosorbent assay (ELISA)
immunoblotting
fibrinogen adsorption assay

Biochem/physiol Actions

Fibrinogen, a blood coagulation protein, is regarded as the central protein in the blood coagulation system.Fibrinogen plays a crucial role in protecting the vascular network against the loss of blood after tissue injury.

Plasmin attacks the Aα chain COOH domain to produce the heterogeneous fragment X. After a series of degradation, it ended with terminal digestion products: fragments D and E which represent the major globular domains in fibrinogen. Mutations in this gene leads to several disorders including hypofibrinogenemia, afibrinogenemia.

The antibody is specific for human fibrinogen and recognizes an epitope sensitive to reduction commonly used in immunoblotting assays. It also reacts with synthetic human fibrinopeptides A and B, fibrinogen related peptides and baboon fibrinogen. No cross-reactivity with bovine, pig, sheep, horse, dog, goat, rabbit, guinea pig, or rat is observed.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item	F9902	F6140	F5766
Sigma-Aldrich F4639 Monoclonal Anti-Fibrinogen antibody produced in mouse	Sigma-Aldrich F9902 Monoclonal Anti-Fibrinogen antibody produced in mouse	Sigma-Aldrich F6140 Monoclonal Anti-Fibronectin, Cellular antibody produced in mouse	Sigma-Aldrich F5766 Monoclonal Anti-Folic Acid antibody produced in mouse
antibody form ascites fluid	antibody form ascites fluid	antibody form ascites fluid	antibody form ascites fluid
biological source mouse	biological source mouse	biological source mouse	biological source mouse
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
species reactivity human, baboon	species reactivity pig, sheep, rabbit, bovine, baboon, human, goat, canine	species reactivity mouse, human, chicken	species reactivity -
Gene Information human ... FGA(2243), FGB(2244), FGG(2266)	Gene Information human ... FGA(2243), FGB(2244), FGG(2266)	Gene Information human ... FN1(2335) mouse ... Fn1(14268)	Gene Information -
clone FG-21, monoclonal	clone 85D4, monoclonal	clone FN-3E2, monoclonal	clone VP-52, monoclonal

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Storage Class

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

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