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G5131

Guanosine 5′-diphospho-D-mannose sodium salt from Saccharomyces cerevisiae

Type I, ≥97% (HPLC)

Synonym(s):

GDP-Man, GDP-mannose

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Size/SKUAvailabilityPrice
10 mg

Available to ship TODAYfromMILWAUKEE

$145.00
50 mg

Available to ship TODAYfromMILWAUKEE

$456.00
100 mg

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$786.00

About This Item

Linear Formula:
C16H23N5O16P2Na2
CAS Number:
Molecular Weight:
649.30
MDL number:
UNSPSC Code:
41106305
PubChem Substance ID:
NACRES:
NA.51
Assay:
≥97% (HPLC)

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type

Type I

Quality Segment

assay

≥97% (HPLC)

storage temp.

−20°C

SMILES string

[Na].NC1=NC(=O)c2ncn(C3OC(COP(O)(=O)OP(O)(=O)OC4OC(CO)C(O)C(O)C4O)C(O)C3O)c2N1

InChI

1S/C16H25N5O16P2.Na.H/c17-16-19-12-6(13(28)20-16)18-3-21(12)14-10(26)8(24)5(34-14)2-33-38(29,30)37-39(31,32)36-15-11(27)9(25)7(23)4(1-22)35-15;;/h3-5,7-11,14-15,22-27H,1-2H2,(H,29,30)(H,31,32)(H3,17,19,20,28);;

InChI key

MEXITZOHWLXZKR-UHFFFAOYSA-N

General description

Guanosine 5′-diphospho-D-mannose (GDP-D-mannose) is present in high cytosolic levels in Saccharomyces cerevisiae. It is crucial for protein mannosylation. GDP-D-mannose is an important precursor to produce GDP-l-fucose.

Application

Guanosine 5′-diphospho-D-mannose sodium salt from Saccharomyces cerevisiae has been used as a nucleotide sugar in transglycosylation enzymatic assay and hydrolysis based catalytic reactions with S-glycosyltransferases (SunS).
Guanosine 5′-diphospho-D-mannose sodium salt has been used as a component of ATP regeneration system for in vitro vesicle formation from Saccharomyces cerevisiae microsomes. It has also been used as a component of the buffer for mannosyl transferase activity assay.

Biochem/physiol Actions

Guanosine diphosphate mannose (GDP-mannose) is a nucleotide sugar substrate for glycosyltransferase (mannosylation) reactions mediated by mannosyltransferases.

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This Item
07508G7252U4625
description

Type I, ≥97% (HPLC)

description

≥94.0% (HPLC)

description

Type VI, ≥92.5%

description

≥98%

assay

≥97% (HPLC)

assay

≥95.0% (HPLC)

assay

≥92.5%

assay

≥98%

Quality Level

200

Quality Level

100

Quality Level

200

Quality Level

300

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

type

Type I

type

-

type

Type VI

type

-


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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Questions

  1. How to dissolve Guanosine 5′-diphospho-D-mannose sodium salt? 

    1 answer
    1. This product is soluble at 50 mg/mL in water.

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