G7017
β-Glucuronidase from Helix pomatia
Type HP-2, aqueous solution, ≥100,000 units/mL
Synonym(s):
β-
Select a Size
| Size/SKU | Availability | Price |
|---|---|---|
1 mL | Check Cart for Availability | $80.10 |
2 mL | Check Cart for Availability | $155.00 |
5 mL | Check Cart for Availability | $282.00 |
10 mL | Check Cart for Availability | $515.00 |
25 mL | Check Cart for Availability | $926.00 |
About This Item
biological source
Helix pomatia
Quality Segment
type
Type HP-2
form
aqueous solution
specific activity
≥100,000 units/mL
secondary activity
≤7,500 units/mL sulfatase
shipped in
wet ice
storage temp.
2-8°C
General description
Application
Learn more
about recent application data generated by Sigma R&D to optimize hydrolysis for different drug classes using enzymes from different sources and the use of a chromatographicaly purified enzyme to reduce the effect of esterase activity resulting in conversion of 6-MAM to Morphine
- Sample preparation for LC/MS through digestion of glucuronide conjugated compounds for biomarker and toxicology research.
- Removal of glucuronide conjugates such as for the preparation of Baicalein.
Biochem/physiol Actions
Microbial beta-glucuronidase found in microbiota can cause re-absorption of metabolites by hydrolysis of glucuronide conjugates of xenobiotic and endobiotic metabolites.
Features and Benefits
- pH optima 4.0 - 5.0.[1]
- Sulfatase pH optima 6.2
- Low Sulfatase activity (<7,500 units/mL).
- Ammonium Sulfate suspension.
- Mollusk-derived beta-glucuronidase.
- Useful for acidic hydrolysis of glucuronides in low pH samples.
Physical form
Analysis Note
Other Notes
1 of 1
This Item | |||
|---|---|---|---|
| description Type HP-2, aqueous solution, ≥100,000 units/mL | description Type HP-2S, aqueous solution, ≥90,000 units/mL | description Type H-1, partially purified powder, ≥300,000 units/g solid | description Type H-5, lyophilized powder, ≥400,000 units/g solid |
| biological source Helix pomatia | biological source - | biological source - | biological source - |
| specific activity ≥100,000 units/mL | specific activity ≥90,000 units/mL | specific activity ≥300,000 units/g solid | specific activity ≥400,000 units/g solid |
| form aqueous solution | form aqueous solution | form partially purified powder | form lyophilized powder |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. −20°C | storage temp. −20°C |
| shipped in wet ice | shipped in - | shipped in - | shipped in - |
| Quality Level 300 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
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signalword
Danger
hcodes
pcodes
Hazard Classifications
Resp. Sens. 1
Storage Class
10 - Combustible liquids
wgk
WGK 1
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