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G7403

Glycine

≥99% (titration), suitable for electron microscopy, BioXtra

Synonym(s):

Aminoacetic acid, Aminoethanoic acid, Glycocoll

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Size/SKUAvailabilityPrice
100 g
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$92.80
250 g
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$165.00
1 kg
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$484.00

About This Item

Linear Formula:
NH2CH2COOH
CAS Number:
Molecular Weight:
75.07
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
200-272-2
MDL number:
Beilstein/REAXYS Number:
635782

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Product Name

Glycine, BioXtra, ≥99% (titration)

product line

BioXtra

Quality Segment

assay

≥99% (titration)

form

powder

technique(s)

electron microscopy: suitable

impurities

Insoluble matter, passes filter test

ign. residue

≤0.05%

loss

≤0.05% loss on drying, HV, 20-26 °C

color

white

pKa (25 °C)

(1) 2.35, (2) 9.60, 2.35

mp

240 °C (dec.) (lit.)

solubility

1 M HCl: 1 M, clear, colorless

anion traces

chloride (Cl-): ≤0.005%, sulfate (SO42-): ≤0.005%

cation traces

Al: ≤0.0005%, As: ≤0.00001%, Ba: ≤0.0005%, Bi: ≤0.0005%, Ca: ≤0.001%, Cd: ≤0.0005%, Co: ≤0.0005%, Cr: ≤0.0005%, Cu: ≤0.0005%, Fe: ≤0.0005%, K: ≤0.005%, Li: ≤0.0005%, Mg: ≤0.0005%, Mn: ≤0.0005%, Mo: ≤0.0005%, NH4+: ≤0.02%, Na: ≤0.02%, Ni: ≤0.0005%, Pb: ≤0.0005%, Sr: ≤0.0005%, Zn: ≤0.0005%

absorption

≤0.04 at 260 in 1 M HCl at 1 M, ≤0.04 at 280 in 1 M HCl at 1 M

SMILES string

NCC(O)=O

UV absorption

λ: 260 nm Amax: ≤0.04, λ: 260 nm Amax: 0.003, λ: 260 nm Amax: 0.006

InChI

1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)

InChI key

DHMQDGOQFOQNFH-UHFFFAOYSA-N

Gene Information

rat ... Grin2a(24409)

Application

Glycine has been used to quench unreacted aldehyde during sample (nuclei) preparation for scanning electron microscope. It has also been used for sample fixation in the process of immunolabeling.

Biochem/physiol Actions

Glycine is a non-essential amino acid. Influx of calcium through the cell membrane is mediated by glycine-gated channel. Glycine participates in the synthesis of porphyrins, purine and serine. It also serves as a competitive agonist for glutamate in binding to the NMDA (N-methyl-D-aspartate) receptors. Glycine synthesis might be increased in rapidly proliferating cancer cells, due to increased demand for the amino acid.
Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.

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This Item
1552741022550046
description

BioXtra, ≥99% (titration)

description

meets analytical specification of Ph. Eur., BP, USP, 99-101% (based on anhydrous substance)

description

ACS reagent, ≥98.5%

description

BioUltra, Molecular Biology, ≥99.0% (NT)

form

powder

form

crystalline powder

form

powder, crystals or granules

form

crystalline

assay

≥99% (titration)

assay

99-101% (based on anhydrous substance)

assay

≥98.5%

assay

≥99.0% (NT)

technique(s)

electron microscopy: suitable

technique(s)

IR spectroscopy: suitable

technique(s)

-

technique(s)

-

product line

BioXtra

product line

-

product line

-

product line

BioUltra

impurities

Insoluble matter, passes filter test

impurities

≤1.0% ninhydrin-positive substances, organic volatile impurities, complies (GC), residual solvents, complies, hydrolyzable substances, complies, ≤0.001% heavy metals (as Pb)

impurities

H2SO4, passes test (darkened), Hydrolyzable subsances, passes test

impurities

RNases, none detected, phosphatases, none detected, insoluble matter, passes filter test, DNases, none detected, proteases, none detected

solubility

1 M HCl: 1 M, clear, colorless

solubility

H2O: soluble 25 gm in 100 ml at 25 degrees c, alcohol: very slightly soluble, diethyl ether: very slightly soluble, pyridine: soluble 164 parts, alcohol: soluble 0.06 gm in 100 gm (Absolute), H2O: soluble 39.1 gm in 100 ml at 50 degrees c

solubility

-

solubility

1 M HCl: 1 M at 20 °C, clear, colorless


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Storage Class

11 - Combustible Solids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)



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