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I0779

Interleukin-2 Soluble Receptor α human

Name: Interleukin-2 Soluble Receptor α human
Brand: SIGMA

>97% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder

Sinonimo/i:

CD25, IL-2 sRα, Tac antigen

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Informazioni su questo articolo

UNSPSC Code:

51111800

NACRES:

NA.32

MDL number:

MFCD01323736

Servizio Tecnico

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Proprietà

biological source

human

Quality Segment

200

recombinant

expressed in NSO cells

assay

>97% (SDS-PAGE)

form

lyophilized powder

potency

0.5-1.0 mg per mL ED₅₀

mol wt

36 kDa by SDS-PAGE

packaging

pkg of 5 μg

impurities

endotoxin, tested

UniProt accession no.

P01589

storage temp.

−20°C

Gene Information

human ... IL2RA(3559)

Descrizione

Biochem/physiol Actions

Interleukin-2 (IL-2), a cytokine, enhances Th (T helper) cell differentiation and effector responses. In addition, it helps in immune tolerance. IL-2 binds to the high affinity receptor, formed of IL2RA (interleukin 2 receptor subunit α), IL2RB (interleukin 2 receptor subunit β) and γ-chain. Polymorphism in IL2RA is associated with multiple sclerosis. Null mutation in IL2RA results in immune dysregulation.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 0.25 mg bovine serum albumin.

Analysis Note

The bioactivity is measured by its ability to inhibit the IL-2-dependent proliferation of a human megakaryocytic leukemic cell line, M07e.

Classe di stoccaggio

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c