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I0779

Interleukin-2 Soluble Receptor α human

>97% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder

Synonym(s):

CD25, IL-2 sRα, Tac antigen

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5 μg
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$228.65

About This Item

UNSPSC Code:
51111800
NACRES:
NA.32
MDL number:

$228.65

List Price$269.00Save 15%

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biological source

human

Quality Segment

recombinant

expressed in NSO cells

assay

>97% (SDS-PAGE)

form

lyophilized powder

potency

0.5-1.0 mg per mL ED50

mol wt

36 kDa by SDS-PAGE

packaging

pkg of 5 μg

impurities

endotoxin, tested

UniProt accession no.

storage temp.

−20°C

Gene Information

human ... IL2RA(3559)

Biochem/physiol Actions

Interleukin-2 (IL-2), a cytokine, enhances Th (T helper) cell differentiation and effector responses. In addition, it helps in immune tolerance. IL-2 binds to the high affinity receptor, formed of IL2RA (interleukin 2 receptor subunit α), IL2RB (interleukin 2 receptor subunit β) and γ-chain. Polymorphism in IL2RA is associated with multiple sclerosis.[1] Null mutation in IL2RA results in immune dysregulation.[2]

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 0.25 mg bovine serum albumin.

Analysis Note

The bioactivity is measured by its ability to inhibit the IL-2-dependent proliferation of a human megakaryocytic leukemic cell line, M07e.

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A9847I5396I2406
description

>97% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder

description

>97% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder

description

IL-1α, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

description

>97% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, suitable for cell culture

biological source

human

biological source

human

biological source

mouse

biological source

human

recombinant

expressed in NSO cells

recombinant

expressed in NSO cells

recombinant

expressed in E. coli

recombinant

expressed in baculovirus infected Sf21 cells

assay

>97% (SDS-PAGE)

assay

>97% (SDS-PAGE)

assay

≥97% (SDS-PAGE)

assay

>97% (SDS-PAGE)

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

100

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

mol wt

36 kDa by SDS-PAGE

mol wt

66 kDa by SDS-PAGE (reducing and non-reducing conditions)

mol wt

18 kDa

mol wt

23 kDa


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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