Key Documents

Anti-Glutamate Receptor NMDAR2B (NR2B) antibody produced in rabbit

Name: Anti-Glutamate Receptor NMDAR2B (NR2B) antibody produced in rabbit
Brand: SIGMA
Price: 697 USD
Availability: InStock

affinity isolated antibody, lyophilized powder

Synonym(s):

Anti-DEE27, Anti-EIEE27, Anti-GluN2B, Anti-MRD6, Anti-NMDAR2B, Anti-NR2B, Anti-NR3, Anti-hNR3

Select a Size

Change View

Size/SKU	Availability	Price
10 μg	Available to ship TODAYfromMILWAUKEE	$820.00 $697.00

About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD01865097

Conjugate:

unconjugated

Clone:

polyclonal

Application:

IHC (f), IP, WB

Citations:

$697.00

List Price$820.00Save 15%

Web-Only Promotion

Available to ship TODAYDetails

A recombinant, preservative-free antibody is available for your target. Try ZRB1242

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

biological source

rabbit

Quality Segment

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

mol wt

antigen 180 kDa

species reactivity

rat, human, mouse

technique(s)

immunohistochemistry (frozen sections): 1:1,000, immunoprecipitation (IP): 3 μL using 200 μg of rat brain, western blot: 1 μg/mL using ³⁵S-Protein A (with ECL dilutions may be higher)

UniProt accession no.

Q13224

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... GRIN2B(2904)
mouse ... Grin2b(14812)
rat ... Grin2b(24410)

Description

General description

Glutamate ionotropic receptor N-methyl-D-aspartate (NMDA) type subunit 2B (GRIN2B) codes for N-methyl D-aspartate receptor subtype 2B (GluN2B). It is an important constituent of the N-methyl D-aspartate receptor protein. GRIN2B gene is located on human chromosome 12p13.1.

Immunogen

C-terminal portion of NR2B (amino acids 984-1104).

Application

Anti-Glutamate Receptor NMDAR2B (NR2B) antibody is suitable for use in immunohistochemistry (1:1,000 dilution, using frozen sections), immunoprecipitation (3 μL using 200 μg of rat brain), and indirect ELISA. The antibody may also be used for western blot (1 μg/mL using (35S)-Protein A) and immunoblot (180 kDa).

Anti-Glutamate Receptor NMDAR2B (NR2B) antibody produced in rabbit has been used in western blotting.

Biochem/physiol Actions

Glutamate ionotropic receptor N-methyl-D-aspartate (NMDA) type subunit 2B (GRIN2B) plays a key role in synaptic plasticity, language acquisition, neural pattern formation and short-term memory. Mutations on GRIN2B gene results in Parkinson′s disease, schizophrenia, bipolar disorder, Alzheimer′s disease and obsessive-compulsive disorder.

The functional N-Methyl-D-Aspartate (NMDA) receptor complex consists of a NMDAR1 (NR1) subunit and atleast one NMDAR2 subunit ranging from NR2A-NR2D. These receptor complexes have been implicated in cochlear functions and neuronal plasticity. The C-terminal end of NR2B receptor may regulate synaptic localization.

Physical form

Lyophilized from ammonium bicarbonate (5 mM).

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item	M266	G8913	M264
Sigma-Aldrich M265 Anti-Glutamate Receptor NMDAR2B (NR2B) antibody produced in rabbit	Sigma-Aldrich M266 Anti-Glutamate Receptor NMDAR2C (NR2C) antibody produced in rabbit	Sigma-Aldrich G8913 Anti-Glutamate Receptor NMDAR1 (NR1) antibody produced in rabbit	Sigma-Aldrich M264 Anti-Glutamate Receptor NMDAR2A (NR2A) antibody produced in rabbit
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody
biological source rabbit	biological source rabbit	biological source rabbit	biological source rabbit
Quality Level 100	Quality Level 200	Quality Level 200	Quality Level 100
technique(s) immunohistochemistry (frozen sections): 1:1,000, western blot: 1 μg/mL using ³⁵S-Protein A (with ECL dilutions may be higher), immunoprecipitation (IP): 3 μL using 200 μg of rat brain	technique(s) immunohistochemistry (frozen sections): 1:1000, immunoprecipitation (IP): 3 μL using 200 μg of rat cerebellum., indirect immunofluorescence: 1:1000 using frozen sections, western blot: 1:1000 using 200 μg cell lysate	technique(s) western blot: 1:2,000 using extract of a rat brain synaptosomal fraction.	technique(s) immunohistochemistry: 1:1,000-1:2,000, immunoprecipitation (IP): 3 μL using 200 μg of rat brain, western blot: 1:1,000
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C

Still not finding the right product?

Try our Product Selector Tool to narrow your options

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.