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Monoclonal Anti-MAP1b antibody produced in mouse

Name: Monoclonal Anti-MAP1b antibody produced in mouse
Brand: SIGMA
Price: 727 USD
Availability: InStock

clone AA6, ascites fluid

Synonym(s):

Anti-MAP1.2, Anti-MAP1X, Anti-MAP5

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Size/SKU	Availability	Price
100 μL	Available to ship TODAYfromMILWAUKEE	$727.00
0.2 mL	Available to ship TODAYfromMILWAUKEE	$786.00

About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD00164682

Conjugate:

unconjugated

Clone:

AA6, monoclonal

Application:

ARR, WB

Citations:

$727.00

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Properties

biological source

mouse

Quality Segment

200

conjugate

unconjugated

antibody form

ascites fluid

antibody product type

primary antibodies

clone

AA6, monoclonal

contains

15 mM sodium azide

species reactivity

human, feline, bovine, hamster, chicken, mouse, rat

technique(s)

microarray: suitable, western blot: 1:500 using a fresh total rat brain extract or an enriched microtubule protein preparation

isotype

IgG1

UniProt accession no.

P46821

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... MAP1B(4131)
mouse ... Mtap1b(17755)
rat ... Map1b(29456)

Description

General description

MAP1b is a microtubule associated protein that interacts with actin filaments. MAP1b regulates microtubule stabilization and the development of axons. It may also act as a scaffolding protein Addition of antibody to microtubule proteins before polymerization in immunoassays results in abnormally short (but otherwise morphologically normal) microtubules. Immunohistochemical staining of brain tissue with the product shows selective labeling of dendritic trees throughout the brain. Monoclonal Anti-MAP1b does not react with tubulin of other microtubule associated proteins.

Monoclonal Anti-MAP1b (MAP5) (mouse IgG1 isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse. Microtubule-associated protein (MAP1B) is the major microtubule associated protein in developing brain which changes its expression during development. In the new born rat brain, it is a major component of microtubules but in the adult its level is ten-fold lower.

Immunogen

rat brain microtubule-associated proteins (MAPs)

Application

Monoclonal Anti-MAP1b antibody produced in mouse has been used in:

immunohistochemistry
immunostaining
fluorescence microscopy

Biochem/physiol Actions

Microtubule-associated protein (MAP1B) is the first MAP to appear in growing axons during development as it is present from the first emergence of the nascent axon from the cell body. Monoclonal Anti-MAP1b may be used to study MAP expression and cytological localization both in tissues and cell lines, under different developmental and environmental circumstances.

Monoclonal Anti-MAP1b antibody is specific for MAP1b in humans, mice, rats, bovines, cats, hamsters and chickens. The antibody does not cross-react with other MAPs or tubulin. Addition of the antibody to microtubule proteins before polymerization results in abnormally short (but otherwise morphologically normal) microtubules. In immunohistochemical staining of brain tissue, the antibody shows selective labeling of neurons with stronger staining of axons, dendrites and cell bodies.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Show Differences

1 of 1

This Item	M4278	M4403	M1406
Sigma-Aldrich M4528 Monoclonal Anti-MAP1b antibody produced in mouse	Sigma-Aldrich M4278 Monoclonal Anti-MAP1 antibody produced in mouse	Sigma-Aldrich M4403 Monoclonal Anti-MAP2 antibody produced in mouse	Sigma-Aldrich M1406 Anti-MAP2 (2a+2b) antibody, Mouse monoclonal
description clone AA6, ascites fluid	description clone HM-1, ascites fluid	description ascites fluid, clone HM-2	description clone AP-20, ascites fluid
Gene Information human ... MAP1B(4131) mouse ... Mtap1b(17755) rat ... Map1b(29456)	Gene Information mouse ... Mtap1a(17754) rat ... Map1a(25152)	Gene Information human ... MAP2(4133) mouse ... Mtap2(17756) rat ... Map2(25595)	Gene Information human ... MAP2(4133) mouse ... Mtap2(17756) rat ... Map2(25595)
species reactivity human, feline, bovine, hamster, chicken, mouse, rat	species reactivity mouse, rat	species reactivity rat, chicken, human, mouse, bovine, quail	species reactivity Xenopus, mouse, quail, human, bovine, rat, aquatic salamander
biological source mouse	biological source mouse	biological source mouse	biological source mouse
antibody form ascites fluid	antibody form ascites fluid	antibody form ascites fluid	antibody form ascites fluid
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
clone AA6, monoclonal	clone HM-1, monoclonal	clone HM-2, monoclonal	clone AP-20, monoclonal

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Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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