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M7945

Mephetyl tetrazole

≥98% (HPLC), oil

Synonym(s):

1-[2-(4-Methoxyphenyl)ethyl]-5-(1-p-tolylcyclopropyl)-1H-tetrazole

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Size/SKUAvailabilityPrice
5 mg

Available to ship TODAYfromMILWAUKEE

$219.00
$186.15

About This Item

Empirical Formula (Hill Notation):
C20H22N4O
CAS Number:
Molecular Weight:
334.41
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
oil

$186.15

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Quality Segment

assay

≥98% (HPLC)

form

oil

color

pale yellow

solubility

DMSO: >5 mg/mL

storage temp.

2-8°C

SMILES string

COc1ccc(CCn2nnnc2C3(CC3)c4ccc(C)cc4)cc1

InChI

1S/C20H22N4O/c1-15-3-7-17(8-4-15)20(12-13-20)19-21-22-23-24(19)14-11-16-5-9-18(25-2)10-6-16/h3-10H,11-14H2,1-2H3

InChI key

VREPWWBWXVLSEF-UHFFFAOYSA-N

Biochem/physiol Actions

Mephetyl tetrazole is a potent and selective Kv1.5 potassium channel blocker.
Mephetyl tetrazole is a potent and selective Kv1.5 potassium channel blocker. IC50 = 330 nM; shows selective atrial prolongation (40%) of effective refractory period (ERP), but no effect on ventricular ERP Kv1.5 channel is a molecular target for the treatment of atrial fibrillation.

Features and Benefits

This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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1 of 1

This Item
SML2295V4515SML2662
assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

form

oil

form

oil

form

powder

form

powder

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: >5 mg/mL

solubility

-

solubility

DMSO: ≥20 mg/mL

solubility

DMSO: 2 mg/mL, clear (warmed)

color

pale yellow

color

colorless to light brown

color

orange

color

white to beige

Quality Level

100

Quality Level

-

Quality Level

100

Quality Level

-


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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