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| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Available to ship TODAYfromMILWAUKEE | $219.00 $186.15 |
About This Item
Empirical Formula (Hill Notation):
C20H22N4O
CAS Number:
Molecular Weight:
334.41
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
oil
$186.15
List Price$219.00Save 15%Web-Only Promotion
Available to ship TODAYDetails
Quality Segment
assay
≥98% (HPLC)
form
oil
color
pale yellow
solubility
DMSO: >5 mg/mL
storage temp.
2-8°C
SMILES string
COc1ccc(CCn2nnnc2C3(CC3)c4ccc(C)cc4)cc1
InChI
1S/C20H22N4O/c1-15-3-7-17(8-4-15)20(12-13-20)19-21-22-23-24(19)14-11-16-5-9-18(25-2)10-6-16/h3-10H,11-14H2,1-2H3
InChI key
VREPWWBWXVLSEF-UHFFFAOYSA-N
Biochem/physiol Actions
Mephetyl tetrazole is a potent and selective Kv1.5 potassium channel blocker.
Mephetyl tetrazole is a potent and selective Kv1.5 potassium channel blocker. IC50 = 330 nM; shows selective atrial prolongation (40%) of effective refractory period (ERP), but no effect on ventricular ERP Kv1.5 channel is a molecular target for the treatment of atrial fibrillation.
Features and Benefits
This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
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This Item | |||
|---|---|---|---|
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| form oil | form oil | form powder | form powder |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility DMSO: >5 mg/mL | solubility - | solubility DMSO: ≥20 mg/mL | solubility DMSO: 2 mg/mL, clear (warmed) |
| color pale yellow | color colorless to light brown | color orange | color white to beige |
| Quality Level 100 | Quality Level - | Quality Level 100 | Quality Level - |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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