Key Documents

Anti-Purinergic Receptor P2Y₁₂ antibody produced in rabbit

Name: Anti-Purinergic Receptor P2Y<SUB>12</SUB> antibody produced in rabbit
Brand: SIGMA
Price: 911 USD
Availability: InStock

affinity isolated antibody, lyophilized powder

Synonym(s):

Anti-ADPG-R, Anti-BDPLT8, Anti-HORK3, Anti-P2T(AC), Anti-P2Y(12)R, Anti-P2Y(AC), Anti-P2Y(ADP), Anti-P2Y(cyc), Anti-P2Y12

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Size/SKU	Availability	Price
200 μL	Check Cart for Availability	$911.00

About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD04975335

Conjugate:

unconjugated

Clone:

polyclonal

Application:

IHC, WB

Citations:

$911.00

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Properties

biological source

rabbit

Quality Segment

200

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

human, mouse, rat

technique(s)

immunohistochemistry: suitable using mouse brain sections, western blot: 1:200 using rat brain membranes or human platelets

UniProt accession no.

Q9H244

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... P2RY12(64805)
mouse ... P2ry12(70839)
rat ... P2ry12(64803)

Description

General description

Purinergic receptor or platelet adenosine 5′-diphosphate (ADP) receptor P2Y12 is a G-protein-coupled receptor. The gene encoding it is localized on human chromosome 3q25.1.

Immunogen

peptide corresponding to amino acid residues 125-142 of human P2Y₁₂. This epitope is highly homologous in rat and mouse (16/18 residues identical).

Application

Anti-Purinergic Receptor P2Y12 antibody produced in rabbit has been used in Western blotting.

Biochem/physiol Actions

Purinergic receptor or platelet adenosine 5′-diphosphate (ADP) receptor P2Y12 has a role in platelet aggregation induced by ADP. Dysfunctional mutations in the protein have been linked with bleeding disorders. Studies have indicated that mice deficient in the P2Y12 receptor show decreased tumor metastasis.

Physical form

Lyophilized from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 0.05% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item	P9122	P0119	ABS1487
Sigma-Aldrich P4871 Anti-Purinergic Receptor P2Y₁₂ antibody produced in rabbit	Sigma-Aldrich P9122 Anti-Purinergic Receptor P2X₇ (extracellular) antibody produced in rabbit	Sigma-Aldrich P0119 Anti-Purinergic Receptor P2Y₁₄ (extracellular) antibody produced in rabbit	Sigma-Aldrich ABS1487 Anti-P2Y12 Receptor
description affinity isolated antibody, lyophilized powder	description affinity isolated antibody, lyophilized powder	description affinity isolated antibody, lyophilized powder	description from rabbit, purified by affinity chromatography
biological source rabbit	biological source rabbit	biological source rabbit	biological source rabbit
antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level -
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. -
Gene Information human ... P2RY12(64805) mouse ... P2ry12(70839) rat ... P2ry12(64803)	Gene Information human ... P2RX7(5027) mouse ... P2rx7(18439) rat ... P2rx7(29665)	Gene Information human ... P2RY14(9934) rat ... P2ry14(171108)	Gene Information human ... P2RY12(64805)

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hcodes

H412

pcodes

P273

Hazard Classifications

Aquatic Chronic 3

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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