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| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Available to ship TODAYfromMILWAUKEE | $73.20 $62.22 |
25 mg | Available to ship TODAYfromMILWAUKEE | $370.00 $314.50 |
About This Item
Empirical Formula (Hill Notation):
C11H6F3NO5
CAS Number:
Molecular Weight:
289.16
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
$62.22
List Price$73.20Save 15%Web-Only Promotion
Available to ship TODAYDetails
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
FC(F)(F)c1[o]c2c([c](c1)=O)c(c(cc2)OC)[N+](=O)[O-]
InChI key
WJUILHMXVGFAIS-UHFFFAOYSA-N
Biochem/physiol Actions
Bragsin2 is a hydration resistant cell penetrant, potent and selective noncompetitive inhibitor of ArfGEF BRAG2 (Afr guanine nucleotide exchange factor BRAG2) that inhibits Arf GTPase activation in vitro and in cells. It binds to pleckstrin homology (PH) domain of BRAG2 and misposition BRAG2 on the membrane. Bragsin2 disrupt the function of the yeast ArfGEF Sec7p. Bragsin2 suppresses tumorsphere formation of some breast cancer stem cell lines including SUM149 and S68.
cell penetrant, potent and selective noncompetitive inhibitor of ArfGEF BRAG2
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This Item | |||
|---|---|---|---|
| description ≥98% (HPLC) | description ≥98% (HPLC) | description ≥98% (HPLC) | description ≥98% (HPLC) |
| form powder | form powder | form powder | form powder |
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility DMSO: 2 mg/mL, clear | solubility DMSO: 20 mg/mL, clear | solubility DMSO: 10 mg/mL, clear | solubility DMSO: 2 mg/mL, clear (warmed) |
| color white to beige | color white to beige | color white to beige | color white to brown |
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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