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SML2606

Bragsin2

≥98% (HPLC)

Synonym(s):

6-Methoxy-5-nitro-2-(trifluoromethyl)-4H-1-benzopyran-4-one

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5 mg

Available to ship TODAYfromMILWAUKEE

$73.20
$62.22
25 mg

Available to ship TODAYfromMILWAUKEE

$370.00
$314.50

About This Item

Empirical Formula (Hill Notation):
C11H6F3NO5
CAS Number:
Molecular Weight:
289.16
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder

$62.22

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assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

FC(F)(F)c1[o]c2c([c](c1)=O)c(c(cc2)OC)[N+](=O)[O-]

InChI key

WJUILHMXVGFAIS-UHFFFAOYSA-N

Biochem/physiol Actions

Bragsin2 is a hydration resistant cell penetrant, potent and selective noncompetitive inhibitor of ArfGEF BRAG2 (Afr guanine nucleotide exchange factor BRAG2) that inhibits Arf GTPase activation in vitro and in cells. It binds to pleckstrin homology (PH) domain of BRAG2 and misposition BRAG2 on the membrane. Bragsin2 disrupt the function of the yeast ArfGEF Sec7p. Bragsin2 suppresses tumorsphere formation of some breast cancer stem cell lines including SUM149 and S68.
cell penetrant, potent and selective noncompetitive inhibitor of ArfGEF BRAG2

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This Item
SML1052SML0947SML2021
description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 20 mg/mL, clear

solubility

DMSO: 10 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear (warmed)

color

white to beige

color

white to beige

color

white to beige

color

white to brown


Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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