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SRP3237

TRAIL from mouse

recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture

Synonym(s):

Apo2 Ligand, TL2, TNF-related apoptosis-inducing Ligand, TNFSF10

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50 μg
Please contact Customer Service for Availability
$410.00

About This Item

NACRES:
NA.32
UNSPSC Code:
12352200
Form:
lyophilized
Assay:
≥95% (HPLC), ≥95% (SDS-PAGE)
Biological source:
mouse
Recombinant:
expressed in E. coli
Mol wt:
20.0 kDa

$410.00

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biological source

mouse

recombinant

expressed in E. coli

assay

≥95% (HPLC), ≥95% (SDS-PAGE)

form

lyophilized

potency

40.0-60.0 ng/mL ED50

mol wt

20.0 kDa

packaging

pkg of 50 μg

technique(s)

cell culture | mammalian: suitable

impurities

<0.1 EU/μg endotoxin, tested

color

white

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

Gene Information

mouse ... TNFSF10(22035)

General description

Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a cytotoxic protein. Recombinant murine TRAIL is a 174 amino acid polypeptide (20.0kDa), consisting of the TNF homologous portion of the extracellular domain of the full length TRAIL protein.

Biochem/physiol Actions

Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) activates rapid apoptosis in tumor cells, but not in normal cells. TRAIL-induced apoptosis is achieved through binding to two death-signaling receptors, death receptor 4 and 5 (DR4 and 5). These receptors belong to the tumor necrosis factor receptor (TNFR) superfamily of transmembrane proteins and contain a cytoplasmic "death domain", which activates the cell′s apoptotic machinery.

Physical form

Lyophilized from 10 mM Sodium Phosphate, pH 7.0.

Preparation Note

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.5-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

Other Notes

MRGGRPQKVA AHITGITRRS NSALIPISKD GKTLGQKIES WESSRKGHSF LNHVLFRNGE LVIEQEGLYY IYSQTYFRFQ EAEDASKMVS KDKVRTKQLV QYIYKYTSYP DPIVLMKSAR NSCWSRDAEY GLYSIYQGGL FELKKNDRIF VSVTNEHLMD LDQEASFFGA FLIN

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SRP8025616374T9701
TRAIL from mouse recombinant, expressed in E. coli, &#8805;95% (SDS-PAGE), &#8805;95% (HPLC), suitable for cell culture

Sigma-Aldrich

SRP3237

TRAIL from mouse

TRAIL, Soluble mouse recombinant, expressed in E. coli, His tagged, &gt;95% (SDS-PAGE)

Sigma-Aldrich

SRP8025

TRAIL, Soluble mouse

TRAIL, Human, Recombinant, E. coli

Sigma-Aldrich

616374

TRAIL, Human, Recombinant, E. coli

TRAIL human recombinant, expressed in E. coli, &#8805;98% (SDS-PAGE and HPLC), lyophilized powder

Sigma-Aldrich

T9701

TRAIL human

description

recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture

description

recombinant, expressed in E. coli, His tagged, >95% (SDS-PAGE)

description

-

description

recombinant, expressed in E. coli, ≥98% (SDS-PAGE and HPLC), lyophilized powder

recombinant

expressed in E. coli

recombinant

expressed in E. coli

recombinant

-

recombinant

expressed in E. coli

biological source

mouse

biological source

mouse

biological source

-

biological source

human

technique(s)

cell culture | mammalian: suitable

technique(s)

-

technique(s)

-

technique(s)

immunofluorescence: suitable

assay

≥95% (HPLC), ≥95% (SDS-PAGE)

assay

>95% (SDS-PAGE)

assay

≥95% (SDS-PAGE)

assay

≥98% (SDS-PAGE and HPLC)

mol wt

20.0 kDa

mol wt

~24 kDa

mol wt

-

mol wt

predicted mol wt ~21 kDa, 19.6 kDa

form

lyophilized

form

liquid

form

liquid

form

lyophilized powder

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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