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D-α-Tocopherol succinate

Name: <SC>D</SC>-α-Tocopherol succinate
Brand: SIGMA

semisynthetic, 1210 IU/g

Synonym(s):

Vitamin E succinate

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About This Item

Empirical Formula (Hill Notation):

C₃₃H₅₄O₅

CAS Number:

4345-03-3

Molecular Weight:

530.78

NACRES:

NA.28

PubChem Substance ID:

24900107

eCl@ss:

34058016

UNSPSC Code:

12352205

EC Number:

224-403-8

MDL number:

MFCD00072055

Beilstein/REAXYS Number:

4038233

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Properties

biological source

semisynthetic

Quality Segment

200

form

powder

specific activity

1210 IU/g

color

white to yellow

storage temp.

room temp

SMILES string

CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2c(C)c(OC(=O)CCC(O)=O)c(C)c(C)c2O1

InChI

1S/C33H54O5/c1-22(2)12-9-13-23(3)14-10-15-24(4)16-11-20-33(8)21-19-28-27(7)31(25(5)26(6)32(28)38-33)37-30(36)18-17-29(34)35/h22-24H,9-21H2,1-8H3,(H,34,35)/t23-,24-,33-/m1/s1

InChI key

IELOKBJPULMYRW-NJQVLOCASA-N

Description

General description

α-Tocopherol succinate is a fat soluble vitamin. α-Tocopherol is a form of vitamin E, which can be obtained through dietary sources. RRR-α-tocopherol is a natural form of α-Tocopherol.

Application

D-α-Tocopherol succinate has been used:

to as a dietary supplement to study its immunomodulatory effects in chicks
as a dietary supplement in pregnant women to evaluate its effects on arsenic exposure
as an antioxidant to investigate concurrent pathways of cell death due to acute exercise

Biochem/physiol Actions

Tocopherols (TCP) (vitamin E) are a series (α, β, γ and δ) of chiral organic molecules that vary in their degree of methylation of the phenol moiety of the chromanol ring. Tocopherols are lipid soluble anti-oxidants that protect cell membranes from oxidative damage. α-Tocopherol is the form of tocopherol preferentially absorbed by homo sapiens. α-Tocopherol succinate is used along the α-Tocopherol acetate, α-Tocopherol nicotinate and other esterified forms as a vitamin E supplement with similar but differential activities.

α-Tocopherol is also called as a radical-chain breaker due to its anti-oxidant property.

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This Item	47782	PHR1029	T1610000
Sigma-Aldrich T3126 D-α-Tocopherol succinate	Supelco 47782 D-α-Tocopherol succinate	Supelco PHR1029 α-Tocopheryl Acid Succinate	T1610000 RRR-α-Tocopheryl hydrogen succinate
description semisynthetic, 1210 IU/g	description analytical standard	description Pharmaceutical Secondary Standard; Certified Reference Material	description European Pharmacopoeia (EP) Reference Standard
biological source semisynthetic	biological source -	biological source -	biological source synthetic
form powder	form -	form -	form solid
storage temp. room temp	storage temp. 2-8°C	storage temp. 2-8°C	storage temp. 2-8°C
color white to yellow	color -	color -	color -
Quality Level 200	Quality Level 100	Quality Level 300	Quality Level -
specific activity 1210 IU/g	specific activity -	specific activity -	specific activity -

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Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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