P9879

Procaine hydrochloride

≥97% (HPLC), powder, Na⁺ channel blocker

• Sinónimos: 4-Aminobenzoic acid 2-diethylaminoethyl ester, p-Aminobenzoic acid diethylaminoethyl ester hydrochloride, Novocaine hydrochloride
• Fórmula lineal: H₂NC₆H₄CO₂CH₂CH₂N(C₂H₅)₂·HCl
• Número CAS: 51-05-8
• Peso molecular: 272.77
• NACRES: NA.77
• PubChem Substance ID: 24278665
• UNSPSC Code: 12352200
• EC Number: 200-077-2
• MDL number: MFCD00013000
• Beilstein/REAXYS Number: 3917802

Propiedades

• Nombre del producto: Procaine hydrochloride, ≥97%
• InChI key: HCBIBCJNVBAKAB-UHFFFAOYSA-N
• InChI: 1S/C13H20N2O2.ClH/c1-3-15(4-2)9-10-17-13(16)11-5-7-12(14)8-6-11;/h5-8H,3-4,9-10,14H2,1-2H3;1H
• SMILES string: Cl.CCN(CC)CCOC(=O)c1ccc(N)cc1
• assay: ≥97%
• form: powder
• mp: 155-156 °C (lit.)
• originator: Celgene
• Quality Level: 200
• Gene Information: human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)

Descripción

Features and Benefits

This compound was developed by Celgene. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Application

Procaine hydrochloride has been used as a component of Krebs Henseleit buffer for incubating the left ventricular cardiac tissue in its resting length. It has also been used as an inducer in M9 media for induction assay.

Biochem/physiol Actions

Procaine is a Na⁺ channel blocker, commonly used as an anesthetic agent and is considered safer than cocaine. It is also useful as a painkiller to treat pain, associated with joints and tendons.

Información de seguridad

• pictograms: GHS06
• signalword: Danger
• hcodes: H301,H317
• pcodes: P261 - P264 - P270 - P280 - P301 + P310 - P302 + P352
• Hazard Classifications: Acute Tox. 3 Oral - Skin Sens. 1
• Clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges