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Merck

07-810

Anti-phospho-Met (Tyr1230/Tyr1234/Tyr1235) Antibody

Upstate®, from rabbit

Synonym(e):

c-Met, cmet, HGFR, RCCP2, met proto-oncogene (hepatocyte growth factor receptor)

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100 μL

€ 438,00

€ 438,00

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Über diesen Artikel

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

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Biologische Quelle

rabbit

Qualitätsniveau

100

Antikörperform

affinity purified immunoglobulin

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Aufgereinigt durch

affinity chromatography

Speziesreaktivität

mouse, human

Speziesreaktivität (Voraussage durch Homologie)

rat (based on 100% sequence homology)

Hersteller/Markenname

Upstate®

Methode(n)

immunocytochemistry: suitable
immunofluorescence: suitable
western blot: suitable

Isotyp

IgG

NCBI-Hinterlegungsnummer

NM_000245.2

UniProt-Hinterlegungsnummer

P08581

Versandbedingung

dry ice

Posttranslationale Modifikation Target

phosphorylation (pTyr1230/pTyr1234/pTyr1235)

Angaben zum Gen

human ... MET(4233)
mouse ... Met(17295)
rat ... Met(24553)

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07-80707-75805-1049
Anti-phospho-Met (Tyr1230/Tyr1234/Tyr1235) Antibody Upstate®, from rabbit

Sigma-Aldrich

07-810

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Anti-phospho-Met (Tyr1003) Antibody Upstate®, from rabbit

Sigma-Aldrich

07-807

Anti-phospho-Met (Tyr1003) Antibody

Anti-Phospho-Flt-1(Tyr1213)-Antikörper Upstate®, from rabbit

Sigma-Aldrich

07-758

Anti-Phospho-Flt-1(Tyr1213)-Antikörper

Anti-Met-Antikörper (extrazellulär), Klon 4F8.2 clone 4F8.2, from mouse

Sigma-Aldrich

05-1049

Anti-Met-Antikörper (extrazellulär), Klon 4F8.2

antibody form

affinity purified immunoglobulin

antibody form

affinity purified immunoglobulin

antibody form

affinity isolated antibody

antibody form

purified antibody

species reactivity

mouse, human

species reactivity

human

species reactivity

bovine, human, goat, sheep, rat, mouse

species reactivity

human

biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

mouse

clone

polyclonal

clone

polyclonal

clone

polyclonal

clone

4F8.2, monoclonal

UniProt accession no.

P08581

UniProt accession no.

P08581

UniProt accession no.

P17948

UniProt accession no.

P08581

technique(s)

immunocytochemistry: suitable, western blot: suitable, immunofluorescence: suitable

technique(s)

western blot: suitable

technique(s)

western blot: suitable

technique(s)

immunohistochemistry: suitable (paraffin), western blot: suitable

Allgemeine Beschreibung

155 kDa

Immunogen

Peptide corresponding to amino acid region encompassing the human, mouse, and rat phospho-c-Met (Tyr1230/Tyr1234/Tyr1235)

Anwendung

Anti-phospho-Met (Tyr1230/Tyr1234/Tyr1235) Antibody is an antibody against phospho-Met (Tyr1230/Tyr1234/Tyr1235) for use in IC, IF & WB.
Immunoblot Analysis: A 1:1000 dilution of this lot detected phospho-Met (Tyr1230/Tyr1234/Tyr1235) in RIPA lysate of HGF treated 293T cells.

Biochem./physiol. Wirkung

Recognizes Met phosphorylated on both Tyr1234/Tyr1235 and Tyr1230/Tyr1234/Tyr1235.

Hinweis zur Analyse

Routinely evaluated by immunoblot.

Rechtliche Hinweise

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

Kwang-Hoon Song et al.
Hepatology (Baltimore, Md.), 46(6), 1993-2002 (2007-10-10)
Bile acid synthesis in the liver is regulated by the rate-limiting enzyme cholesterol 7alpha-hydroxylase (CYP7A1). Transcription of the CYP7A1 gene is inhibited by bile acids and cytokines. The rate of bile acid synthesis is reduced immediately after partial hepatectomy and
Federica Chiara et al.
The Journal of biological chemistry, 278(31), 29352-29358 (2003-05-15)
The met oncogene, encoding the high affinity hepatocyte growth factor receptor, is the only known gene inherited in human cancer that is invariably associated with somatic duplication of the mutant locus. Intriguingly, mutated Met requires ligand stimulation in order to
A selective c-met inhibitor blocks an autocrine hepatocyte growth factor growth loop in ANBL-6 cells and prevents migration and adhesion of myeloma cells
Hov, H?kon, et al
Clinical cancer research : an official journal of the American Association for Cancer Research, 10, 6686-6694 (2004)
c-Met modulates RPE migratory response to laser-induced retinal injury.
Kasaoka, M; Ma, J; Lashkari, K
Testing null
P Longati et al.
Oncogene, 9(1), 49-57 (1994-01-01)
The tyrosine kinase encoded by the MET proto-oncogene (p190MET) is the receptor for Hepatocyte Growth Factor/Scatter Factor (HGF/SF). Previous work has shown that autophosphorylation of p190MET enhances its enzymatic activity and that the major phosphorylation site is Tyr1235, located in
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