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189482

Autocamtide-2 Related Inhibitory Peptide, Myristoylated

≥97% (HPLC), CaM kinase II inhibitor, lyophilized

Synonym(e):

Autocamtide-2 Related Inhibitory Peptide, Myristoylated, Myristoylated AIP, Myr-N-KKALRRQGAVDAL-OH

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Größe/SKUVerfügbarkeitPreis
500 μg
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€ 272,00

Über diesen Artikel

Empirische Formel (Hill-System):
C78H142N22O20
Molekulargewicht:
1708.10
UNSPSC Code:
12352202
NACRES:
NA.77
Assay:
≥97% (HPLC)
Form:
lyophilized
Storage condition:
OK to freeze, desiccated (hygroscopic)

€ 272,00


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Produktname

Autocamtide-2 Related Inhibitory Peptide, Myristoylated, The Autocamtide-2 Related Inhibitory Peptide, Myristoylated controls the biological activity of calmodulin-dependent protein kinase II. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

Quality Segment

assay

≥97% (HPLC)

form

lyophilized

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, desiccated (hygroscopic)

solubility

water: 1 mg/mL

shipped in

ambient

storage temp.

−20°C

General description

This peptide corresponds to AIP (Cat. No. 189480 ) which has been myristoylated at the N-terminus, thus enhancing its cell-permeability.

Biochem/physiol Actions

Cell permeable: yes
Primary Target
Calmodulin-Dependent Protein Kinase (CaM Kinase)-2
Product does not compete with ATP.
Reversible: no
Target IC50: 40 nM against cam Kinase-2

Physical form

Supplied as a trifluoroacetate salt.

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Gailly, P., et al. 1998. Cell Calcium 24, 293.
Ishida, A., and Fujisawa, H. 1995. J. Biol. Chem.270, 2163.
Ishida, A., et al. 1995. Biochem. Biophys. Res. Commun.212, 806.
Myr-N-Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Ala-Val-Asp-Ala-Leu-OH

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

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Dieser Artikel
476485476475539604
description

The Autocamtide-2 Related Inhibitory Peptide, Myristoylated controls the biological activity of calmodulin-dependent protein kinase II. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

description

PKA Inhibitor 14-22 Amide is myristoylated at the N-terminus that enhances its cell-permeability. The non-myristoylated version is shown to be a specific inhibitor of PKA (Ki = 36 nM).

description

The PKC Inhibitor, EGF-R Fragment 651-658, Myristoylated controls the biological activity of PKC. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

description

The PKCη Pseudosubstrate Inhibitor, Myristoylated controls the biological activity of PKCη. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

form

lyophilized

form

lyophilized

form

lyophilized solid

form

lyophilized solid

assay

≥97% (HPLC)

assay

≥95% (HPLC)

assay

≥97% (HPLC)

assay

≥95% (HPLC)

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

solubility

water: 1 mg/mL

solubility

water: 1 mg/mL

solubility

water: 5 mg/mL

solubility

water: 1 mg/mL


Lagerklasse

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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Questions

  1. Do you send with the negative control (scramble sequence) ? How are we ordering scramble sequence?

    1 answer
    1. This product does not include a negative control (scramble sequence). Currently, no such negative control is available.

      Please see the Custom Peptide Synthesis at the link below:
      https://www.sigmaaldrich.com/technical-documents/technical-article/protein-biology/protein-and-nucleic-acid-interactions/custom-peptides

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